Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5733017 | 0.92 | PKM (0.53) | ALDH1A1PKML3MBTL1MAPTMEN1 | |
| SCHEMBL30024173 | 0.92 | PKM (0.53) | ALDH1A1PKML3MBTL1MAPTMEN1 | |
| SCHEMBL6629500 | 0.88 | BACE1 (0.50) | ALDH1A1PKML3MBTL1MAPTMEN1 | |
| SCHEMBL6629498 | 0.88 | BACE1 (0.50) | ALDH1A1PKML3MBTL1MAPTMEN1 | |
| SCHEMBL10844233 | 0.82 | MEN1 (0.49) | ALDH1A1PKML3MBTL1MAPTMEN1 | |
| SCHEMBL7683609 | 0.81 | ALDH1A1 (0.64) | ALDH1A1PKMMAPTMEN1KMT2A | |
| SCHEMBL5991259 | 0.81 | LTA4H (0.49) | ALDH1A1PKML3MBTL1MAPTMEN1 | |
| SCHEMBL27563285 | 0.81 | MEN1 (0.48) | PKML3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL27551196 | 0.80 | MEN1 (0.55) | ALDH1A1PKML3MBTL1MAPTMEN1 | |
| SCHEMBL6361504 | 0.80 | MEN1 (0.56) | PKML3MBTL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1272841-A | Novel lactam metalloprotease inhibitors | DU PONT PHARM CO (US) | 2000-11-08 | — | — | CN | disclosed |