Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10850936 | 0.79 | KDM4E (0.39) | ALDH1A1HPGDTSHRCYP1A2KDM4E | |
| SCHEMBL10845658 | 0.76 | P2RX3 (0.43) | ALDH1A1HPGDKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10845673 | 0.75 | KDM4E (0.35) | ALDH1A1HPGDHTTKDM4EPOLB | |
| SCHEMBL10847525 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4EPOLBRAB9ANPC1 | |
| SCHEMBL10847287 | 0.73 | ALDH1A1 (0.38) | ALDH1A1HTTKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10847777 | 0.68 | CYP1A2 (0.51) | ALDH1A1HPGDTSHRCYP1A2HTT | |
| SCHEMBL12529593 | 0.65 | KDM4E (0.37) | ALDH1A1HPGDTSHRKDM4EPOLB | |
| SCHEMBL2514326 | 0.63 | ALDH1A1 (1.00) | ALDH1A1HPGDTSHRKDM4EPOLB | |
| SCHEMBL18336649 | 0.62 | CYP1A2 (0.45) | ALDH1A1CYP1A2HTTKDM4EPOLB | |
| SCHEMBL2440905 | 0.62 | CYP1A2 (0.45) | ALDH1A1CYP1A2HTTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609660-A | Substituted carboxy-thiazolo[3,2-a]pyrimidine derivatives | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1986-09-02 | — | — | US | disclosed |
| US-4558046-A | ANTIALLERGENS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1985-12-10 | — | — | US | disclosed |