Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.73 |
| ▸ | BCHE | P06276 | 4/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | PDE5A | O76074 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875649 | 0.87 | MEN1 (0.54) | ACHEBCHECYP1A2CYP3A4PDE5A | |
| SCHEMBL9875605 | 0.86 | ACHE (0.55) | ACHEBCHECYP1A2CYP3A4PDE5A | |
| SCHEMBL9876195 | 0.85 | CYP1A2 (0.51) | ACHEBCHECYP1A2CYP3A4PDE5A | |
| SCHEMBL8984077 | 0.84 | KMT2A (0.67) | ACHEBCHEKDM4EPOLBRAD52 | |
| Water SCHEMBL9876037 | 0.84 | CYP1A2 (0.50) | ACHEBCHECYP1A2CYP3A4PDE5A | |
| Water SCHEMBL9876033 | 0.84 | CYP1A2 (0.50) | ACHEBCHECYP1A2CYP3A4PDE5A | |
| SCHEMBL9875000 | 0.83 | KDM4E (0.57) | ACHEBCHECYP1A2CYP3A4APP | |
| SCHEMBL9875619 | 0.82 | KDM4E (0.54) | ACHEBCHECYP1A2CYP3A4PDE5A | |
| SCHEMBL10846227 | 0.82 | KDM4E (0.51) | ACHEBCHECYP1A2CYP3A4PDE5A | |
| SCHEMBL9875822 | 0.81 | KMT2A (0.57) | ACHEBCHEAPPGAAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631286-A | MEMORY ENHANCERS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-12-23 | — | — | US | disclosed |