Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851402 | 0.89 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3LTA4HMAOA | |
| SCHEMBL17459374 | 0.86 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3LTA4HMAOB | |
| SCHEMBL10846556 | 0.84 | HRH4 (0.44) | SLC6A2SLC6A4SLC6A3ALDH1A1HTR2A | |
| SCHEMBL11048736 | 0.78 | ESR1 (0.54) | SLC6A2SLC6A4SLC6A3POLBMAOB | |
| SCHEMBL17468994 | 0.76 | LTA4H (0.40) | SLC6A2SLC6A4SLC6A3LTA4HGUSB | |
| SCHEMBL17459356 | 0.75 | GUSB (0.40) | SLC6A2SLC6A4SLC6A3LTA4HPOLB | |
| SCHEMBL17459409 | 0.75 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3LTA4HGUSB | |
| SCHEMBL17468761 | 0.74 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3MAOBKDM4E | |
| SCHEMBL17469070 | 0.72 | GUSB (0.41) | SLC6A2SLC6A4SLC6A3LTA4HGUSB | |
| SCHEMBL17459317 | 0.71 | F10 (0.49) | SLC6A2SLC6A4SLC6A3POLBGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318909-A | Benzoxazocines | JOHN WYETH & BROTHER LIMITED (GB) | 1982-03-09 | — | — | US | claimed |
| US-4626522-A | Benzoxazocines intermediates | JOHN WYETH & BROTHER LIMITED (GB) | 1986-12-02 | — | — | US | disclosed |
| US-4318909-A | Benzoxazocines | JOHN WYETH & BROTHER LIMITED (GB) | 1982-03-09 | — | — | US | disclosed |