SCHEMBL17459409

SCHEMBL17459409

CCN1Cc2ccccc2OC(c2ccc(Cl)cc2)C1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
LTA4H P09960 14/20 0.40
GUSB P08236 1/20 0.38
L3MBTL4 Q8NA19 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17469070 0.96 GUSB (0.41) SLC6A2SLC6A4SLC6A3LTA4HGUSB
SCHEMBL17469027 0.89 MAOB (0.42) SLC6A2SLC6A4SLC6A3LTA4H
SCHEMBL17468345 0.89 MAOB (0.42) SLC6A2SLC6A4SLC6A3LTA4H
SCHEMBL17459287 0.87 LTA4H (0.38) SLC6A2SLC6A4SLC6A3LTA4H
SCHEMBL17459277 0.87 LTA4H (0.38) SLC6A2SLC6A4SLC6A3LTA4H
SCHEMBL17459303 0.87 LTA4H (0.38) SLC6A2SLC6A4SLC6A3LTA4H
SCHEMBL17459309 0.87 LTA4H (0.40) SLC6A2SLC6A4SLC6A3LTA4H
SCHEMBL17469153 0.86 HTR2C (0.38) SLC6A2SLC6A4SLC6A3LTA4HGUSB
SCHEMBL17459470 0.85 LTA4H (0.40) SLC6A2SLC6A4SLC6A3LTA4HL3MBTL1
SCHEMBL17469000 0.85 MAOB (0.50) SLC6A4LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016012333-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-01-28 WO disclosed
WO-2016012333-A1 PESTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2016-01-28 WO disclosed