Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849346 | 0.90 | ALDH1A1 (0.42) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11214622 | 0.89 | ALDH1A1 (0.41) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10851145 | 0.88 | GAA (0.45) | NPC1MAPTRAB9ASMN1; SMN2EGFR | |
| SCHEMBL10849969 | 0.77 | ALDH1A1 (0.44) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11060811 | 0.76 | PRKCZ (0.56) | EGFRMEN1KMT2A | |
| SCHEMBL11058379 | 0.74 | PRKCZ (0.57) | — | |
| SCHEMBL908494 | 0.74 | CA1 (0.56) | MAPTEGFRALDH1A1MEN1KMT2A | |
| SCHEMBL908259 | 0.71 | PRKCZ (0.41) | EGFR | |
| SCHEMBL10846803 | 0.71 | PRKCZ (0.41) | EGFRALDH1A1MEN1KMT2A | |
| SCHEMBL6294304 | 0.70 | MEN1 (0.64) | MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622401-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |