Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 11/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL908494 | 0.94 | CA1 (0.56) | PRKCZEGFRERBB2CA1CA2 | |
| SCHEMBL11058379 | 0.92 | PRKCZ (0.57) | PRKCZCA1CA2PDE5A | |
| SCHEMBL11068412 | 0.89 | MEN1 (0.54) | PRKCZEGFRERBB2CA1CA2 | |
| SCHEMBL11060046 | 0.85 | PRKCZ (0.51) | PRKCZMEN1KMT2AATMMAOB | |
| SCHEMBL11060055 | 0.84 | EGFR (0.53) | PRKCZEGFRERBB2CA1CA2 | |
| SCHEMBL11104257 | 0.84 | EGFR (0.57) | PRKCZEGFRERBB2ATMPDE5A | |
| SCHEMBL908137 | 0.84 | PRKCZ (0.58) | PRKCZEGFRCA1CA2ATM | |
| SCHEMBL11068397 | 0.83 | PRKCZ (0.52) | PRKCZEGFRERBB2PDE5A | |
| SCHEMBL8640819 | 0.81 | PRKCZ (0.48) | PRKCZCA1CA2PDE5A | |
| SCHEMBL908259 | 0.81 | PRKCZ (0.41) | PRKCZEGFRERBB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4432991-A | ANALGESICS, FUNGICIDE, BACTERICIDE, ANTIINFLAMMATORY, OR ANTIARTHRITIC AGENTS, ANTIALLERGENS, AND BRONCHODILATOR | AMERICAN CYANAMID COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4360680-A | ANALGESIC, ANTIINFLAMMATORY AGENT, FUNGICIDE AND BACTERICIDE | AMERICAN CYANAMID COMPANY (US) | 1982-11-23 | — | — | US | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |