Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135552 | 0.79 | TSHR (0.46) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL28438742 | 0.79 | TSHR (0.46) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Water SCHEMBL3700992 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL863480 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28759713 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL336735 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3577655 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Iodide SCHEMBL6657020 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL2139803 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A | |
| Iodide SCHEMBL27498959 | 0.76 | TSHR (0.43) | DNM1TSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617409-A | Aminomethyltriorganotin compounds, preferably α-mono or disubstituted; and the method of preparation | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1986-10-14 | — | — | US | disclosed |