SCHEMBL863480

SCHEMBL863480

CCCC[Sn](CCCC)(CCCC)CC[Sn](CCCC)(CCCC)CCCC

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.43
LMNA P02545 3/20 0.43
THRB P10828 1/20 0.40
ALDH1A1 P00352 4/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC22A1 O15245 3/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DNM1 Q05193 5/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28438742 0.96 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL135552 0.96 TSHR (0.46) TSHRLMNATHRBALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL28759713 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL2139803 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL28092082 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
SCHEMBL3577655 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Water SCHEMBL3700992 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Hydrochloric Acid SCHEMBL336735 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Iodide SCHEMBL6657020 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1
Iodide SCHEMBL27498959 0.92 TSHR (0.43) TSHRLMNATHRBALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8829202-B2 Condensed polycyclic aromatic compound, aromatic polymer, and method for synthesizing aromatic compound TEIJIN LIMITED (JP) 2014-09-09 US disclosed
US-20140187792-A1 CONDENSED POLYCYCLIC AROMATIC COMPOUND, AROMATIC POLYMER, AND METHOD FOR SYNTHESIZING AROMATIC COMPOUND TEIJIN LIMITED (JP) 2014-07-03 US disclosed
EP-2740735-A1 CONDENSED POLYCYCLIC AROMATIC COMPOUND, AROMATIC POLYMER, AND METHOD FOR SYNTHESIZING AROMATIC COMPOUND Teijin Limited (JP) 2014-06-11 EP disclosed
EP-2438104-B1 FUSED BITHIOPHENE-VINYLENE POLYMERS BASF SE (DE) 2014-04-30 EP disclosed
US-8466460-B2 Fused bithiophene-vinylene polymers BASF SE (DE) 2013-06-18 US disclosed
US-8287775-B2 Photochromic material KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2012-10-16 US disclosed
EP-2438104-A1 FUSED BITHIOPHENE-VINYLENE POLYMERS BASF SE (DE) 2012-04-11 EP disclosed
US-20120074410-A1 FUSED BITHIOPHENE-VINYLENE POLYMERS POLYERA CORPORATION (US) 2012-03-29 US disclosed
WO-2011102599-A1 PHOTOCHROMIC MATERIAL KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2011-08-25 WO disclosed
US-20110198546-A1 PHOTOCHROMIC MATERIAL KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2011-08-18 US disclosed
WO-2010149451-A1 FUSED BITHIOPHENE-VINYLENE POLYMERS BASF SE (DE) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187792-A1 CONDENSED POLYCYCLIC AROMATIC COMPOUND, AROMATIC POLYMER, AND METHOD FOR SYNTHESIZING AROMATIC COMPOUND PAH, C9, CCNB2 TSHR 3417/4885LMNA 1091/4885THRB 4630/4885
US-20110198546-A1 PHOTOCHROMIC MATERIAL PPOX, RAD51, DCLRE1A TSHR 2807/4885LMNA 3675/4885THRB 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.