Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135552 | 0.96 | TSHR (0.46) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL28438742 | 0.96 | TSHR (0.46) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28759713 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL863480 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Iodide SCHEMBL27498959 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Water SCHEMBL3700992 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Iodide SCHEMBL6657020 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL2139803 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL3577655 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL28092082 | 0.92 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116375984-A | Water-soluble conjugated high-molecular polymer and preparation method thereof | 西京学院 | 2023-07-04 | — | — | CN | claimed |
| CN-108445061-B | Determination method for detecting tin and compounds thereof in air | 广东华晟安全职业评价有限公司 | 2020-10-02 | — | — | CN | claimed |
| CN-105198907-A | Preparation method and application of two-dimensional aza-indacene-based organic solar cell donor materials | BEIJING INST TECHNOLOGY | 2015-12-30 | — | — | CN | claimed |
| WO-2024088398-A1 | PHOSPHORUS-CONTAINING COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2024-05-02 | — | — | WO | disclosed |
| CN-116640165-A | Near infrared two-region fluorescent compound with aggregation-induced emission property, and preparation method and application thereof | 西藏大学 | 2023-08-25 | — | — | CN | disclosed |
| CN-116375984-A | Water-soluble conjugated high-molecular polymer and preparation method thereof | 西京学院 | 2023-07-04 | — | — | CN | disclosed |
| WO-2021123055-A1 | A PROCESS FOR THE PREPARATION OF TRIBUTYLTIN CHLORIDE WITH HIGH PURITY | PMC VLISSINGEN, B.V (US) | 2021-06-24 | — | — | WO | disclosed |
| EP-3838906-A1 | A PROCESS FOR THE PREPARATION OF TRIBUTYLTIN CHLORIDE WITH HIGH PURITY | LANXESS Organometallics GmbH (DE) | 2021-06-23 | — | — | EP | disclosed |
| CN-108445061-B | Determination method for detecting tin and compounds thereof in air | 广东华晟安全职业评价有限公司 | 2020-10-02 | — | — | CN | disclosed |
| US-10239886-B2 | Polymer compound and organic semiconductor device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-03-26 | — | — | US | disclosed |
| US-20190036028-A1 | COMPOSITION AND ORGANIC THIN FILM TRANSISTOR USING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2019-01-31 | — | — | US | disclosed |
| EP-2336132-B1 | MORPHOLINOPURINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2014-01-01 | — | — | EP | disclosed |
| US-8309546-B2 | Morpholinopurine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20120071476-A1 | MORPHOLINOPURINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
| US-8097622-B2 | Morpholinopurine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-17 | — | — | US | disclosed |
| EP-2336132-A1 | MORPHOLINOPURINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2011-06-22 | — | — | EP | disclosed |
| US-20100130492-A1 | MORPHOLINOPURINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| CN-100575372-C | Continuous polymerization reactor | BRIDGESTONE CORP | 2009-12-30 | — | — | CN | disclosed |
| US-20090203920-A1 | METHOD FOR ISOLATING 5-SUBSTITUTED TETRAZOLES | SANOCHEMIA PHARMAZEUTIKA AG (AT) | 2009-08-13 | — | — | US | disclosed |
| CN-1942490-A | Continuous polymerization reactor | BRIDGESTONE CORP (JP) | 2007-04-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130492-A1 | MORPHOLINOPURINE DERIVATIVES | MTOR, RICTOR, PIK3R1 | TSHR 2037/4885LMNA 4352/4885THRB 3166/4885 |
| US-20120071476-A1 | MORPHOLINOPURINE DERIVATIVES | MTOR, RICTOR, PIK3R1 | TSHR 2037/4885LMNA 4352/4885THRB 3166/4885 |
| US-10239886-B2 | Polymer compound and organic semiconductor device using the same | ZYX, OR10J3, ZRANB2 | TSHR 2984/4885LMNA 3909/4885THRB 3531/4885 |
| US-20090203920-A1 | METHOD FOR ISOLATING 5-SUBSTITUTED TETRAZOLES | TH, CASP5, TYR | TSHR 1418/4885LMNA 889/4885THRB 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.