Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 8/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 8/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.34 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | MSN | P26038 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10846477 | 1.00 | AKR1B1 (0.36) | AKR1B1ALDH1A1KCNE1KCNQ1ABCC9 | |
| SCHEMBL10848293 | 0.82 | KDM4E (0.38) | KCNE1KCNQ1KDM4E | |
| SCHEMBL10848280 | 0.82 | KDM4E (0.38) | KCNE1KCNQ1KDM4E | |
| SCHEMBL10849342 | 0.80 | KDM4E (0.56) | KCNE1KCNQ1MEN1KMT2AKDM4E | |
| SCHEMBL10846473 | 0.80 | KCNE1 (0.34) | ALDH1A1KCNE1KCNQ1ABCC9MEN1 | |
| SCHEMBL11085099 | 0.80 | KCNE1 (0.34) | ALDH1A1KCNE1KCNQ1ABCC9MEN1 | |
| SCHEMBL10849336 | 0.80 | KDM4E (0.56) | KCNE1KCNQ1MEN1KMT2AKDM4E | |
| SCHEMBL10848203 | 0.80 | AKR1B1 (0.38) | AKR1B1ALDH1A1ABCC9MEN1KMT2A | |
| SCHEMBL10848193 | 0.80 | AKR1B1 (0.38) | AKR1B1ALDH1A1ABCC9MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11611531 | 0.75 | KCNE1 (0.48) | KCNE1KCNQ1ABCC9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4629734-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1986-12-16 | — | — | US | claimed |