SCHEMBL10847010

SCHEMBL10847010

CC(C)(C=O)CCc1c[nH]nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11192016 0.82 MEN1 (0.35)
SCHEMBL10456702 0.76 CYP1A2 (0.35)
SCHEMBL10740901 0.74
SCHEMBL17108682 0.72
SCHEMBL16852766 0.72
Methylamine SCHEMBL28882609 0.71
SCHEMBL5531414 0.69 PPARA (0.39)
SCHEMBL1647676 0.69
SCHEMBL2002939 0.68 ADH1B (0.31)
SCHEMBL5538955 0.68 ACLY (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0032200-B1 SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES BAYER AG (DE) 1983-07-13 EP claimed
EP-0031911-B1 SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-KETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES BAYER AG (DE) 1982-11-17 EP claimed
EP-0032200-A1 Substituted triazolylmethyl-tert.-butyl-carbinols, process for their preparation and their use as plant protecting agents as well as intermediates BAYER AG (DE) 1981-07-22 EP claimed
EP-0031911-A2 Substituted triazolylmethyl-tert.-butyl-ketones, process for their preparation and their use as plant protecting agents as well as intermediates BAYER AG (DE) 1981-07-15 EP claimed
EP-0103798-B1 SUBSTITUTED AZOLYLALKYL-T.BUTYL KETONES AND CARBINOLS BAYER AG (DE) 1986-12-30 EP disclosed
US-4603140-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1986-07-29 US disclosed
EP-0103798-A2 Substituted azolylalkyl-t.butyl ketones and carbinols BAYER AG (DE) 1984-03-28 EP disclosed
EP-0032200-B1 SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES BAYER AG (DE) 1983-07-13 EP disclosed
EP-0031911-B1 SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-KETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES BAYER AG (DE) 1982-11-17 EP disclosed
EP-0031911-B1 SUBSTITUTED TRIAZOLYLMETHYL-TERT.-BUTYL-KETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PLANT PROTECTING AGENTS AS WELL AS INTERMEDIATES BAYER AG (DE) 1982-11-17 EP disclosed
EP-0057357-A2 Plant growth stunting agent BAYER AG (DE) 1982-08-11 EP disclosed
EP-0032200-A1 Substituted triazolylmethyl-tert.-butyl-carbinols, process for their preparation and their use as plant protecting agents as well as intermediates BAYER AG (DE) 1981-07-22 EP disclosed
EP-0031911-A2 Substituted triazolylmethyl-tert.-butyl-ketones, process for their preparation and their use as plant protecting agents as well as intermediates BAYER AG (DE) 1981-07-15 EP disclosed
EP-0031911-A2 Substituted triazolylmethyl-tert.-butyl-ketones, process for their preparation and their use as plant protecting agents as well as intermediates BAYER AG (DE) 1981-07-15 EP disclosed
EP-0031911-A2 Substituted triazolylmethyl-tert.-butyl-ketones, process for their preparation and their use as plant protecting agents as well as intermediates BAYER AG (DE) 1981-07-15 EP disclosed