⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740901 | 0.77 | — | — | |
| SCHEMBL21182588 | 0.77 | — | — | |
| SCHEMBL10456702 | 0.76 | CYP1A2 (0.35) | — | |
| SCHEMBL14420554 | 0.72 | — | — | |
| SCHEMBL10847010 | 0.72 | — | — | |
| SCHEMBL22635893 | 0.72 | — | — | |
| SCHEMBL4799019 | 0.69 | DUT (0.35) | — | |
| SCHEMBL10624770 | 0.68 | FDPS (0.46) | — | |
| SCHEMBL19686516 | 0.68 | — | — | |
| SCHEMBL11948261 | 0.67 | GBA1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015148379-A1 | MONOBACTAM ORGANIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-10-01 | — | — | WO | disclosed |
| US-20150266867-A1 | MONOBACTAM ORGANIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2015-09-24 | — | — | US | disclosed |