Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | LIPE | Q05469 | 4/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.37 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.37 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10855208 | 0.88 | MAPK1 (0.48) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10851965 | 0.86 | TSHR (0.50) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10847282 | 0.86 | RAB9A (0.52) | LMNASMN1; SMN2LIPETDP1ALDH1A1 | |
| SCHEMBL11052171 | 0.84 | LMNA (0.48) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10846359 | 0.84 | TSHR (0.62) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10847036 | 0.84 | LMNA (0.47) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10854845 | 0.83 | LMNA (0.46) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10957034 | 0.83 | LMNA (0.46) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL11011256 | 0.81 | TSHR (0.57) | TSHRLMNACYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL11005079 | 0.80 | TDP1 (0.54) | TSHRLMNACYP2C9APEX1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071572-B1 | DERIVATIVES OF 2-NITRO-4- OR-5-PYRIDYLOXY-PHENYLPHOSPHONIC ACID, PROCESS FOR THEIR PREPARATION, THEIR USE AS HERBICIDES AND/OR REGULATORS OF PLANT GROWTH AND/OR MICROBICIDES, AS WELL AS THE INTERMEDIATES USED FOR THEIR PREPARATION, THE PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | claimed |
| US-4451284-A | Derivatives of 2-nitro-4- or -5-pyridyloxyphenylphosphonic acid, the preparation thereof, the use thereof as herbicides and/or plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | claimed |
| US-4610980-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1986-09-09 | — | — | US | disclosed |
| US-4451284-A | Derivatives of 2-nitro-4- or -5-pyridyloxyphenylphosphonic acid, the preparation thereof, the use thereof as herbicides and/or plant growth regulators | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |