Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.41 |
| ▸ | LIPE | Q05469 | 4/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052171 | 0.88 | LMNA (0.48) | LMNATSHRCYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10854172 | 0.88 | LMNA (0.48) | LMNASMN1; SMN2LIPEALDH1A1HTT | |
| SCHEMBL10851965 | 0.87 | TSHR (0.50) | LMNATSHRCYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10859868 | 0.87 | LIPE (0.42) | LMNATSHRCYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10855208 | 0.87 | MAPK1 (0.48) | LMNATSHRCYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10847036 | 0.84 | LMNA (0.47) | LMNATSHRCYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10855519 | 0.84 | PPARG (0.37) | LMNASMN1; SMN2MAPK1PIN1LIPE | |
| SCHEMBL10957034 | 0.84 | LMNA (0.46) | LMNATSHRCYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10847158 | 0.83 | TSHR (0.52) | LMNATSHRCYP2C9APEX1SMN1; SMN2 | |
| SCHEMBL10854686 | 0.82 | TDP1 (0.57) | LMNATSHRSMN1; SMN2MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563310-A | HERBICIDES | ZOECON CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0065374-A1 | Substituted phosphinates and phosphinothioates and their use for the control of weeds | ZOECON CORPORATION (US) | 1982-11-24 | — | — | EP | disclosed |