Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10812882 | 0.92 | NPSR1 (0.67) | NPSR1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL2497926 | 0.88 | NPSR1 (0.76) | NPSR1ALDH1A1LMNAL3MBTL1NR1I3 | |
| SCHEMBL2513419 | 0.86 | NPSR1 (0.64) | NPSR1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL10810550 | 0.84 | NPSR1 (0.53) | NPSR1KDM4EKMT2AMEN1ADORA2A | |
| SCHEMBL10808538 | 0.83 | NPSR1 (0.79) | NPSR1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL4546890 | 0.76 | RAB9A (0.55) | ALDH1A1L3MBTL1HPGDRAB9AKDM4E | |
| SCHEMBL10809881 | 0.73 | NPSR1 (0.54) | NPSR1ALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL14665605 | 0.73 | NPSR1 (0.46) | NPSR1ALDH1A1MAPTL3MBTL1HPGD | |
| SCHEMBL10812182 | 0.73 | NPSR1 (0.54) | NPSR1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL2501529 | 0.72 | NPSR1 (0.83) | NPSR1ALDH1A1LMNAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616014-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0077983-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-04 | — | — | EP | disclosed |