SCHEMBL10847465

SCHEMBL10847465

CCCCP(CCCC)CCC(C)(C)c1cc(OC)ccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
ALDH1A1 P00352 3/20 0.42
CNR2 P34972 5/20 0.40
CNR1 P21554 1/20 0.40
ERN1 O75460 1/20 0.40
XBP1 P17861 1/20 0.40
ATM Q13315 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
BACE1 P56817 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221406 0.85 CNR2 (0.53) GAAALDH1A1CNR2CNR1ERN1
SCHEMBL11786492 0.83 GAA (0.50) GAAALDH1A1CNR2CNR1ERN1
SCHEMBL18944155 0.80 ALDH1A1 (0.53) GAAALDH1A1ERN1XBP1ATM
SCHEMBL221405 0.75 ALDH1A1 (0.51) GAAALDH1A1ERN1XBP1ATM
SCHEMBL9519087 0.73 GAA (0.46) GAAALDH1A1CNR2XBP1ATM
SCHEMBL10845567 0.72 CNR2 (0.46) GAACNR2CNR1XBP1ATM
SCHEMBL11799609 0.72 GAA (0.43) GAAALDH1A1CNR2CNR1XBP1
SCHEMBL12405380 0.72 ALDH1A1 (0.51) GAAALDH1A1ERN1KDM4EMEN1
SCHEMBL9149517 0.72 ALDH1A1 (0.48) GAAALDH1A1ERN1L3MBTL1KDM4E
SCHEMBL10825797 0.72 CNR1 (0.46) GAAALDH1A1CNR2CNR1ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4631252-A PHOTOGRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1986-12-23 US disclosed
US-4616082-A PHOTOGRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1986-10-07 US disclosed
US-4549015-A PHOTOHRAPHIC STABILIZERS CIBA-GEIGY AG (CH) 1985-10-22 US disclosed
EP-0098241-B1 HYDROQUINONE ETHERS AND A PROCESS FOR PREPARING THEM CIBA-GEIGY AG (CH) 1985-10-02 EP disclosed