Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847649 | 1.00 | PTGS1 (0.32) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL10849188 | 0.79 | MEN1 (0.32) | PTGS1PTGS2MAPTMEN1ALDH1A1 | |
| SCHEMBL10849180 | 0.79 | MEN1 (0.32) | PTGS1PTGS2MAPTMEN1ALDH1A1 | |
| SCHEMBL2200875 | 0.79 | CA1 (0.37) | CA12CA1CA2CA9MAPT | |
| SCHEMBL11723057 | 0.71 | MEN1 (0.43) | PTGS1PTGS2CA12CA1CA2 | |
| SCHEMBL3585261 | 0.69 | CA2 (0.42) | CA12CA1CA2CA9MAPT | |
| SCHEMBL23531735 | 0.68 | PTK2 (0.36) | CA12CA1CA2CA9MAPT | |
| SCHEMBL10848517 | 0.68 | — | — | |
| SCHEMBL10848522 | 0.68 | — | — | |
| SCHEMBL10493783 | 0.66 | ALDH1A1 (0.38) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60139691-A | — | — | None | — | — | JP | disclosed |
| US-4620868-A | N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-3[halo-substituted ethenyl (or propenyl)]-2-thiophenesulfonamides useful as herbicides | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1986-11-04 | — | — | US | disclosed |
| JP-S60139691-A | SUBSTITUTED THIOPHENESULFONAMIDE BASED COMPOUND AND HERBICIDE CONTAINING THE SAME | ISHIHARA SANGYO KAISHA LTD | 1985-07-24 | — | — | JP | disclosed |