Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 8/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851651 | 0.87 | PKM (0.40) | P2RX7RXRARXRBRXRGKDM4E | |
| SCHEMBL10850856 | 0.86 | NOTUM (0.36) | P2RX7RXRARXRBRXRGCNR2 | |
| SCHEMBL838856 | 0.85 | KMT2A (0.51) | P2RX7DRD2HTR2ARXRARXRB | |
| SCHEMBL10616320 | 0.76 | PTGS1 (0.52) | P2RX7DRD2HTR2ARXRARXRB | |
| SCHEMBL10851281 | 0.76 | RXRA (0.35) | RXRARXRBRXRGKDM4EKMT2A | |
| SCHEMBL10851575 | 0.76 | RXRA (0.37) | RXRARXRBRXRGKDM4EKMT2A | |
| SCHEMBL4756363 | 0.76 | P2RX7 (0.57) | P2RX7KDM4E | |
| SCHEMBL10850429 | 0.75 | KDM4E (0.45) | RXRARXRBRXRGCNR2CNR1 | |
| SCHEMBL11094559 | 0.74 | PTGS1 (0.45) | P2RX7DRD2HTR2ADRD1DRD4 | |
| SCHEMBL26120479 | 0.73 | SMN1; SMN2 (0.47) | RXRARXRBRXRGKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563210-A | PRE-AND POSTEMERGENCE | ELI LILLY AND COMPANY (US) | 1986-01-07 | — | — | US | claimed |
| US-4563210-A | PRE-AND POSTEMERGENCE | ELI LILLY AND COMPANY (US) | 1986-01-07 | — | — | US | disclosed |