SCHEMBL10850652

SCHEMBL10850652

ClCc1[c]cc2ccccc2c1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
CYP2A6 P11509 2/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL455936 0.80 CYP2A6 (0.45) CYP2A6CYP1A2KMT2AMEN1CA1
SCHEMBL2003901 0.78 HTR2A (0.39) CYP2A6CYP1A2CA1CA2
SCHEMBL1973142 0.77 CYP2A6 (0.38) CYP2A6CYP1A2KMT2AMEN1
SCHEMBL5748025 0.75 CYP2A6 (0.41) CYP2A6CYP1A2KMT2AMEN1
SCHEMBL28010056 0.75 TDP1 (0.37) CYP2A6CYP1A2
SCHEMBL27848664 0.75 CALM1 (0.42) CYP2A6CYP1A2KMT2A
SCHEMBL28004178 0.74 KDM4E (0.39) L3MBTL1CYP2A6CYP1A2KMT2AMEN1
SCHEMBL2256514 0.74 TLR8 (0.40) CYP2A6CYP1A2KMT2AMEN1
SCHEMBL28039386 0.72 SMN1; SMN2 (0.41) L3MBTL1CYP2A6CYP1A2KMT2AMEN1
SCHEMBL2253153 0.71 KCNH2 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4622397-A HERBICIDES CIBA-GEIGY CORPORATION (US) 1986-11-11 US disclosed