Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455936 | 0.75 | CYP2A6 (0.45) | KDM4ETDP1MEN1KMT2AATM | |
| SCHEMBL2003901 | 0.74 | HTR2A (0.39) | KDM4ETDP1MAPTCA1CA2 | |
| SCHEMBL10850652 | 0.74 | L3MBTL1 (0.39) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL1973142 | 0.72 | CYP2A6 (0.38) | KDM4ETDP1MEN1KMT2AATM | |
| SCHEMBL28010056 | 0.71 | TDP1 (0.37) | TDP1MAPTCYP1A2CYP2A6 | |
| SCHEMBL27848664 | 0.71 | CALM1 (0.42) | KMT2ACYP1A2CYP2A6 | |
| SCHEMBL5748025 | 0.71 | CYP2A6 (0.41) | KDM4ETDP1MEN1KMT2AATM | |
| SCHEMBL11040769 | 0.70 | KDM4E (0.47) | KDM4ETDP1MEN1KMT2AATM | |
| SCHEMBL645519 | 0.69 | CA1 (0.38) | KDM4ECA1CA2CYP1A2CYP2A6 | |
| SCHEMBL2256514 | 0.69 | TLR8 (0.40) | TDP1MEN1KMT2AATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102317296-B | Fused aromatic PTP-1B inhibitors | KANEQ PHARMA INC | 2015-05-27 | — | — | CN | disclosed |
| CN-104411710-A | Fused aromatic phosphonate derivatives as precursors to ptp-1b inhibitors | KANEQ PHARMA INC | 2015-03-11 | — | — | CN | disclosed |