Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 7/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849661 | 0.81 | GAA (0.47) | BCHEALDH1A1 | |
| SCHEMBL10853398 | 0.77 | CASR (0.48) | MEN1KMT2AHTR1AGPR55TP53 | |
| SCHEMBL4217666 | 0.73 | RAB9A (0.43) | MEN1KMT2AHTR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10847499 | 0.73 | MEN1 (0.47) | MEN1KMT2AATMBCHEHTR1A | |
| SCHEMBL10032816 | 0.70 | MEN1 (0.85) | MEN1KMT2AATMBCHESMN1; SMN2 | |
| SCHEMBL12131075 | 0.70 | MEN1 (0.85) | MEN1KMT2AATMBCHESMN1; SMN2 | |
| SCHEMBL10851269 | 0.70 | MEN1 (0.44) | MEN1KMT2AATMBCHEHTR1A | |
| SCHEMBL9835348 | 0.69 | LMNA (0.50) | MEN1KMT2AHTR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10032820 | 0.69 | BCHE (0.64) | MEN1KMT2AATMBCHESMN1; SMN2 | |
| SCHEMBL10032817 | 0.69 | HTR2A (0.62) | MEN1KMT2AATMBCHEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563458-A | CIRCULATORY SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-01-07 | — | — | US | disclosed |