Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813540 | 1.00 | PSMD14 (0.60) | PSMD14ALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL9813569 | 0.91 | PSMD14 (0.61) | PSMD14ALDH1A1TDP1POLBKMT2A | |
| SCHEMBL9813566 | 0.91 | PSMD14 (0.61) | PSMD14ALDH1A1TDP1POLBKMT2A | |
| SCHEMBL10851899 | 0.86 | PSMD14 (0.55) | PSMD14ALDH1A1TDP1KDM4EPOLB | |
| SCHEMBL10851908 | 0.86 | PSMD14 (0.55) | PSMD14ALDH1A1TDP1KDM4EPOLB | |
| Ralitoline SCHEMBL635346 | 0.85 | PSMD14 (0.55) | PSMD14ALDH1A1TDP1GAA | |
| Ralitoline SCHEMBL9813595 | 0.85 | PSMD14 (0.55) | PSMD14ALDH1A1TDP1GAA | |
| SCHEMBL9813617 | 0.83 | ALDH1A1 (0.71) | PSMD14ALDH1A1TDP1POLBKMT2A | |
| SCHEMBL9813610 | 0.83 | ALDH1A1 (0.71) | PSMD14ALDH1A1TDP1POLBKMT2A | |
| SCHEMBL9813607 | 0.81 | PSMD14 (0.51) | PSMD14ALDH1A1TDP1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563471-A | CENTRAL NERVOUS SYSTEM DISORDERS | WARNER-LAMBERT COMPANY (US) | 1986-01-07 | — | — | US | disclosed |