Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | PPOX | P50336 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10862805 | 0.89 | TDP1 (0.45) | TDP1PDE7AS1PR4TSHRALDH1A1 | |
| SCHEMBL10857434 | 0.87 | MEN1 (0.58) | TDP1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL11048611 | 0.87 | TDP1 (0.56) | TDP1PDE7AS1PR4MAPK1TSHR | |
| SCHEMBL10857037 | 0.86 | TDP1 (0.58) | TDP1PDE7AS1PR4MAPK1TSHR | |
| SCHEMBL10852632 | 0.85 | TDP1 (0.60) | TDP1PDE7AS1PR4MAPK1TSHR | |
| SCHEMBL10854845 | 0.82 | LMNA (0.46) | TDP1MAPK1TSHRALDH1A1LMNA | |
| SCHEMBL11049687 | 0.82 | TDP1 (0.50) | TDP1PDE7AS1PR4ALDH1A1MEN1 | |
| SCHEMBL10861112 | 0.82 | TDP1 (0.61) | TDP1PDE7AS1PR4MAPK1TSHR | |
| SCHEMBL10855519 | 0.81 | PPARG (0.37) | TDP1S1PR4MAPK1ALDH1A1MEN1 | |
| SCHEMBL10951063 | 0.79 | TDP1 (0.58) | TDP1PDE7AS1PR4MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563310-A | HERBICIDES | ZOECON CORPORATION (US) | 1986-01-07 | — | — | US | disclosed |
| EP-0065374-A1 | Substituted phosphinates and phosphinothioates and their use for the control of weeds | ZOECON CORPORATION (US) | 1982-11-24 | — | — | EP | disclosed |