Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10951206 | 0.92 | PDE7A (0.55) | TDP1S1PR4PDE7AMAPK1ALDH1A1 | |
| SCHEMBL10955819 | 0.89 | TDP1 (0.44) | TDP1S1PR4PDE7AMAPK1TSHR | |
| SCHEMBL10857037 | 0.88 | TDP1 (0.58) | TDP1S1PR4PDE7AMAPK1TSHR | |
| SCHEMBL10955246 | 0.87 | PDE7A (0.41) | TDP1S1PR4PDE7AMAPK1TSHR | |
| SCHEMBL10854686 | 0.87 | TDP1 (0.57) | TDP1S1PR4PDE7AMAPK1TSHR | |
| SCHEMBL10853995 | 0.86 | TDP1 (0.60) | TDP1MAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL10861112 | 0.84 | TDP1 (0.61) | TDP1S1PR4PDE7AMAPK1TSHR | |
| SCHEMBL10852632 | 0.83 | TDP1 (0.60) | TDP1S1PR4PDE7AMAPK1TSHR | |
| SCHEMBL10953054 | 0.82 | ALDH1A1 (0.48) | TDP1S1PR4MAPK1ALDH1A1MEN1 | |
| SCHEMBL11052171 | 0.81 | LMNA (0.48) | TDP1S1PR4MAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456465-A | HERBICIDES | ZOECON CORPORATION (US) | 1984-06-26 | — | — | US | disclosed |