Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Riboflavin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.74 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 7/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.87 |
| ▸ | USP2 | O75604 | 4/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.87 |
| ▸ | HAT1 | O14929 | 4/20 | 0.87 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.87 |
| ▸ | HTT | P42858 | 4/20 | 0.87 |
| ▸ | RECQL | P46063 | 3/20 | 0.87 |
| ▸ | CASP7 | P55210 | 3/20 | 0.87 |
| ▸ | MAPT | P10636 | 3/20 | 0.87 |
| ▸ | CASP1 | P29466 | 2/20 | 0.87 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.87 |
| ▸ | TST | Q16762 | 2/20 | 0.87 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.87 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.87 |
| ▸ | LMNA | P02545 | 1/20 | 0.87 |
| ▸ | HBB | P68871 | 1/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Riboflavin SCHEMBL535031 | 0.98 | MEN1 (0.87) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL27866166 | 0.98 | MEN1 (0.87) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL50154 | 0.98 | MEN1 (0.87) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL367680 | 0.97 | MEN1 (0.85) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL1085509 | 0.97 | MEN1 (0.89) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL5477646 | 0.97 | MEN1 (0.89) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL2241206 | 0.95 | MEN1 (0.89) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL296802 | 0.95 | MEN1 (0.89) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL21805317 | 0.95 | MEN1 (0.89) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL618997 | 0.95 | MEN1 (0.89) | MEN1KMT2AUSP2KDM4EHAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080038142-A1 | Method for Forming Powder Molding Product and Mold Apparatus for Powder Molding | MITSUBISHI MATERIALS PMG CORPORATION (JP) | 2008-02-14 | — | — | US | claimed |
| US-20070081913-A1 | Iron base sintered alloy having highly densified and hardened surface, and producing method thereof | MITSUBISHI MATERIALS CORPORATION (JP) | 2007-04-12 | — | — | US | claimed |
| EP-1724037-A1 | METHOD OF FORMING POWDER COMPACT AND MOLD ASSEMBLY FOR POWDER COMPACTION | Mitsubishi Materials PMG Corporation (JP) | 2006-11-22 | — | — | EP | claimed |
| EP-1640469-A1 | IRON BASE SINTERED ALLOY EXHIBITING HIGH SURFACE DENSIFICATION AND HIGH SURFACE HARDNESS, AND METHOD FOR PRODUCTION THEREOF | MITSUBISHI MATERIALS CORPORATION (JP) | 2006-03-29 | — | — | EP | claimed |
| US-20060022371-A1 | Method for forming compact from powder and mold apparatus for powder forming | MITSUBISHI MATERIALS CORPORATION (JP) | 2006-02-02 | — | — | US | claimed |
| EP-1563986-A1 | METHOD FOR FORMING COMPACT FROM POWDER AND MOLD APPARATUS FOR POWDER FORMING | MITSUBISHI MATERIALS CORPORATION (JP) | 2005-08-17 | — | — | EP | claimed |
| CN-117384873-A | Glycerol phosphate oxidase mutant and screening method, preparation method and application thereof | 武汉瀚海新酶生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-115247158-B | Glycerol phosphate oxidase mutant and screening method, preparation method and application thereof | 武汉瀚海新酶生物科技有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-115247158-A | Glycerol phosphate oxidase mutant and screening method, preparation method and application thereof | 武汉瀚海新酶生物科技有限公司 | 2022-10-28 | — | — | CN | disclosed |
| EP-1563986-B1 | METHOD FOR FORMING COMPACT FROM POWDER | DIAMET CORP (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-8153053-B2 | Method for forming compact from powder and sintered product | DIAMET CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100135841-A1 | METHOD FOR FORMING COMPACT FROM POWDER AND SINTERED PRODUCT | DIAMET CORPORATION (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20080038142-A1 | Method for Forming Powder Molding Product and Mold Apparatus for Powder Molding | MITSUBISHI MATERIALS PMG CORPORATION (JP) | 2008-02-14 | — | — | US | disclosed |
| US-20070081913-A1 | Iron base sintered alloy having highly densified and hardened surface, and producing method thereof | MITSUBISHI MATERIALS CORPORATION (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1724037-A1 | METHOD OF FORMING POWDER COMPACT AND MOLD ASSEMBLY FOR POWDER COMPACTION | Mitsubishi Materials PMG Corporation (JP) | 2006-11-22 | — | — | EP | disclosed |
| EP-1640469-A1 | IRON BASE SINTERED ALLOY EXHIBITING HIGH SURFACE DENSIFICATION AND HIGH SURFACE HARDNESS, AND METHOD FOR PRODUCTION THEREOF | MITSUBISHI MATERIALS CORPORATION (JP) | 2006-03-29 | — | — | EP | disclosed |
| US-20060022371-A1 | Method for forming compact from powder and mold apparatus for powder forming | MITSUBISHI MATERIALS CORPORATION (JP) | 2006-02-02 | — | — | US | disclosed |
| EP-1563986-A1 | METHOD FOR FORMING COMPACT FROM POWDER AND MOLD APPARATUS FOR POWDER FORMING | MITSUBISHI MATERIALS CORPORATION (JP) | 2005-08-17 | — | — | EP | disclosed |