Riboflavin

Riboflavin

SCHEMBL50154

Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(C[C@H](O)[C@H](O)[C@H](O)CO)c2cc1C.O=P([O-])(O)O.[Na+]

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Riboflavin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.74
ADRA1A known ✓ P35348 1/20 0.74
MEN1 O00255 7/20 0.87
KMT2A Q03164 7/20 0.87
USP2 O75604 4/20 0.87
KDM4E B2RXH2 4/20 0.87
HAT1 O14929 4/20 0.87
RBBP7 Q16576 4/20 0.87
HTT P42858 4/20 0.87
RECQL P46063 3/20 0.87
CASP7 P55210 3/20 0.87
MAPT P10636 3/20 0.87
CASP1 P29466 2/20 0.87
BRCA1 P38398 2/20 0.87
HSD17B10 Q99714 2/20 0.87
TST Q16762 2/20 0.87
TDP1 Q9NUW8 2/20 0.87
ALDH1A1 P00352 2/20 0.87
LMNA P02545 1/20 0.87
HBB P68871 1/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Riboflavin SCHEMBL535031 1.00 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL27866166 1.00 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL367680 0.99 MEN1 (0.85) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL1085508 0.98 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL296802 0.97 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL21805317 0.97 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL618997 0.97 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL367681 0.96 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL2241206 0.95 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL1085509 0.95 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2021 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056386-A Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-19 CN claimed
CN-122030612-A Shear-resistant slow-release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-15 CN claimed
US-12365850-B2 Water-miscible functional fluid, undiluted stock of water-miscible functional fluid, sterilizer for water-miscible functional fluid, and method of sterilizing water-miscible function fluid YUSHIRO CHEMICAL INDUSTRY CO., LTD. (JP) 2025-07-22 US claimed
CN-120053465-A Preparation method of multivitamin injection 山东力诺制药有限公司 2025-05-30 CN claimed
CN-119326884-B Nano-composite photosensitizer for transepithelial ion-introduced cornea collagen crosslinking, and preparation method and application thereof 温州医科大学附属眼视光医院 2025-05-06 CN claimed
EP-4308161-B1 OPHTHALMIC PREPARATIONS FOR PHOTO-CROSSLINKING REACTIONS LIGI TECNOLOGIE MEDICALI S R L (IT) 2025-04-30 EP claimed
CN-119769630-A Traditional Chinese medicine anti-coccidiosis ruminant compound feed 大庆市天赐饲料有限公司 2025-04-08 CN claimed
CN-119701092-A Collagen gel microsphere, and preparation method and application thereof 深圳福楼拜生物科技有限公司 2025-03-28 CN claimed
EP-4500612-A1 POLYSULFIDE-BASED AQUEOUS REDOX FLOW BATTERY WITH SOLUBLE ORGANIC CATALYST The Chinese University of Hong Kong (HK) 2025-02-05 EP claimed
CN-119326884-A Nano-composite photosensitizer for transepithelial ion-introduced cornea collagen crosslinking, and preparation method and application thereof 温州医科大学附属眼视光医院 2025-01-21 CN claimed
CN-1390118-A Glucose and insulin liquid compositions for intravenous infusion GANGAL HANAMARADDI T (IN) 2003-01-08 CN claimed
EP-1231907-A2 DEXTROSE AND INSULIN FLUID FORMULATION FOR INTRAVENOUS INFUSION Gangal, Hanamaraddi T. (IN) 2002-08-21 EP claimed
WO-2001035943-A2 DEXTROSE AND INSULIN FLUID FORMULATION FOR INTRAVENOUS INFUSION GANGAL HANAMARADDI T (IN) 2001-05-25 WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
CN-1140992-A Flavin derivatives as anti-viral agents RADOPATH LTD (GB) 1997-01-22 CN claimed
EP-0739208-A1 FLAVIN DERIVATIVES AS ANTI-VIRAL AGENTS RADOPATH LIMITED (GB) 1996-10-30 EP claimed
WO-1995011028-A1 FLAVIN DERIVATIVES AS ANTI-VIRAL AGENTS RADOPATH LIMITED (GB) 1995-04-27 WO claimed
EP-0497177-B1 Vitamin containing formulations and their production HOFFMANN LA ROCHE (CH) 1995-01-18 EP claimed
US-5185336-A Spray drying aqueous solution or suspension HOFFMANN-LA ROCHE INC. (US) 1993-02-09 US claimed
US-5044091-A Frozen first and second liquid freeze dried together SANKYO COMPANY, LIMITED (JP) 1991-09-03 US claimed