Riboflavin

Riboflavin

SCHEMBL618997

Cc1cc2nc3c(=O)[nH]c(=O)nc-3n(C[C@@H](O)[C@@H](O)[C@@H](O)CO)c2cc1C.O=P([O-])([O-])[O-].[Na+].[Na+].[Na+]

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Riboflavin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 known ✓ P07550 1/20 0.72
ADRA1A known ✓ P35348 1/20 0.72
MEN1 O00255 7/20 0.89
KMT2A Q03164 7/20 0.89
USP2 O75604 4/20 0.89
KDM4E B2RXH2 4/20 0.89
HAT1 O14929 4/20 0.89
RBBP7 Q16576 4/20 0.89
HTT P42858 4/20 0.89
RECQL P46063 3/20 0.89
CASP7 P55210 3/20 0.89
MAPT P10636 3/20 0.89
CASP1 P29466 2/20 0.89
BRCA1 P38398 2/20 0.89
HSD17B10 Q99714 2/20 0.89
TST Q16762 2/20 0.89
TDP1 Q9NUW8 2/20 0.89
ALDH1A1 P00352 2/20 0.89
LMNA P02545 1/20 0.89
HBB P68871 1/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Riboflavin SCHEMBL21805317 1.00 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL296802 1.00 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL367681 0.99 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL5477646 0.98 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL2241206 0.98 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL1085509 0.98 MEN1 (0.89) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL535031 0.97 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL27866166 0.97 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL50154 0.97 MEN1 (0.87) MEN1KMT2AUSP2KDM4EHAT1
Riboflavin SCHEMBL367680 0.96 MEN1 (0.85) MEN1KMT2AUSP2KDM4EHAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 325 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056386-A Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-19 CN claimed
CN-122030612-A Shear-resistant slow-release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-15 CN claimed
CN-118738489-B Preparation method of molecular-driven high-performance sulfur-based flow battery 长沙理工大学 2025-01-14 CN claimed
CN-118453553-A Application of gingerol vanillylacetone in preparation of medicine for treating colorectal cancer 华中科技大学同济医学院附属协和医院 2024-08-09 CN claimed
WO-2024148248-A1 DERMAL REJUVENATION COMPOSITION COMPRISING PLACENTA DERIVED BIOMATERIAL AND USES THEREOF CELULARITY INC. (US) 2024-07-11 WO claimed
CN-110974721-B Face-repairing powder ball and preparation method thereof 娇时日化(杭州)股份有限公司 2022-10-21 CN claimed
CN-112245403-B Phosphodiesterase-4 inhibitor and oral solid composition thereof 杭州朱养心药业有限公司 2022-04-22 CN claimed
US-20210315799-A1 Composition for Promoting Differentiation or Proliferation of Human Adipose-Derived Stem Cell LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2021-10-14 US claimed
CN-112638357-A Composition for promoting differentiation or proliferation of human adipose-derived stem cells 株式会社LG生活健康 2021-04-09 CN claimed
CN-112305107-A Apremilast composition of phosphodiesterase-4 inhibitor and quality detection method 杭州朱养心药业有限公司 2021-02-02 CN claimed
CN-102206233-A Industrial preparation method for riboflavine sodium phosphate HUBEI GUANGJI PHARMACEUTICAL CO LTD 2011-10-05 CN claimed
CN-101518516-B Sodium riboflavin phosphate lyophilized powder for injection and preparation method thereof JINXIU HUANG 2010-09-29 CN claimed
CN-101518516-A Sodium riboflavin phosphate lyophilized powder for injection and preparation method thereof JINXIU HUANG 2009-09-02 CN claimed
EP-1824349-A1 PRODUCTION PROCESS FOR MAKING DIETETIC PRODUCT - ORAL TABLETS CONTAINING BEEBREAD AND VITAMIN C Mogorovic, Milos (YU) 2007-08-29 EP claimed
EP-1819239-A1 DRY CONCENTRATE FOR MAKING DIETETIC SOFT DRINK WITH BEEBREAD AND ITS PRODUCTION PROCESS Mogorovic, Milos (YU) 2007-08-22 EP claimed
US-20070081913-A1 Iron base sintered alloy having highly densified and hardened surface, and producing method thereof MITSUBISHI MATERIALS CORPORATION (JP) 2007-04-12 US claimed
WO-2006066283-A1 PRODUCTION PROCESS FOR MAKING DIETETIC PRODUCT - ORAL TABLETS CONTAINING BEEBREAD AND VITAMIN C MOGOROVIC MILOS (YU) 2006-06-22 WO claimed
WO-2006066284-A1 DRY CONCENTRATE FOR MAKING DIETETIC SOFT DRINK WITH BEEBREAD AND ITS PRODUCTION PROCESS MOGOROVIC MILOS (YU) 2006-06-22 WO claimed
EP-1640469-A1 IRON BASE SINTERED ALLOY EXHIBITING HIGH SURFACE DENSIFICATION AND HIGH SURFACE HARDNESS, AND METHOD FOR PRODUCTION THEREOF MITSUBISHI MATERIALS CORPORATION (JP) 2006-03-29 EP claimed
US-5044091-A Frozen first and second liquid freeze dried together SANKYO COMPANY, LIMITED (JP) 1991-09-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210315799-A1 Composition for Promoting Differentiation or Proliferation of Human Adipose-Derived Stem Cell LRBA, FABP4, ALOX15 ADRB2 1799/4885ADRA1A 1787/4885MEN1 679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.