Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 13/20 | 0.40 |
| ▸ | ITGA2 | P17301 | 13/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17600402 | 0.81 | MAPT (0.62) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL1252254 | 0.78 | GAA (0.62) | GAAMAPTITGB1ITGA2 | |
| SCHEMBL2080900 | 0.78 | GAA (0.62) | GAAMAPTITGB1ITGA2 | |
| SCHEMBL1252255 | 0.78 | GAA (0.62) | GAAMAPTITGB1ITGA2 | |
| SCHEMBL11035541 | 0.77 | TDP2 (0.45) | GAAMAPTITGB1ITGA2 | |
| SCHEMBL10854713 | 0.77 | TDP2 (0.45) | GAAMAPTITGB1ITGA2 | |
| SCHEMBL10854682 | 0.76 | GAA (0.44) | GAAMAPTITGB1ITGA2 | |
| SCHEMBL27579143 | 0.76 | GAA (0.60) | GAAMAPTALDH1A1HPGD | |
| SCHEMBL7444115 | 0.72 | EGLN1 (0.44) | GAAMAPT | |
| SCHEMBL31369696 | 0.72 | EGLN1 (0.44) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563306-A | CONSCIOUSNESS DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0134582-A2 | Novel peptides and process for preparing the same and pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1985-03-20 | — | — | EP | disclosed |