Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 6/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10854713 | 1.00 | TDP2 (0.45) | TDP2ITGB1ITGA2TDP1CYP3A4 | |
| SCHEMBL30213424 | 0.83 | GAA (0.55) | TDP1PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL4537304 | 0.83 | GAA (0.55) | TDP1PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL16116108 | 0.83 | GAA (0.55) | TDP1PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL10293160 | 0.79 | GAA (0.54) | TDP1PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL29697818 | 0.79 | GAA (0.54) | TDP1PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL16115726 | 0.79 | GAA (0.54) | TDP1PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8247179 | 0.79 | PNMT (0.57) | TDP2TDP1CYP3A4HTR1ACAPN9 | |
| SCHEMBL10855641 | 0.77 | GAA (0.44) | ITGB1ITGA2GAAMAPT | |
| SCHEMBL15623045 | 0.75 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134582-A2 | Novel peptides and process for preparing the same and pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1985-03-20 | — | — | EP | disclosed |