Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859044 | 0.82 | CHRM2 (0.57) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL4936216 | 0.82 | CHRM2 (0.61) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL13304408 | 0.82 | CHRM2 (0.61) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL30463042 | 0.81 | ALDH1A1 (0.62) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL10849479 | 0.81 | CHRM2 (0.72) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL3339536 | 0.81 | ALDH1A1 (0.62) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL30463043 | 0.81 | ALDH1A1 (0.62) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL11031607 | 0.81 | CHRM2 (0.56) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| SCHEMBL10854331 | 0.80 | CHRM2 (0.75) | CHRM2ADRA2BDRD3SIGMAR1HRH3 | |
| Hydrochloric Acid SCHEMBL31346808 | 0.80 | CHRM2 (0.59) | CHRM2ADRA2BDRD3SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4563454-A | ASTHMA, RHINITIS, DERMATITIS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| US-4277474-A | DERMATITIS, RHINITIS, ASTHMA | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |
| EP-0004000-A1 | New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1979-09-19 | — | — | EP | disclosed |