Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13183455 | 0.85 | RAB9A (0.32) | RAB9ASMN1; SMN2DUSP3L3MBTL1ALDH1A1 | |
| SCHEMBL12344019 | 0.82 | PAK4 (0.35) | RAB9ASMN1; SMN2DUSP3L3MBTL1ALDH1A1 | |
| SCHEMBL1586647 | 0.81 | ALDH1A1 (0.33) | RAB9ASMN1; SMN2DUSP3L3MBTL1ALDH1A1 | |
| Hydrazine SCHEMBL28089137 | 0.78 | ERN1 (0.31) | ALDH1A1MAPTGAAHTTERN1 | |
| SCHEMBL23723791 | 0.74 | — | — | |
| SCHEMBL21803067 | 0.71 | — | — | |
| SCHEMBL1085685 | 0.71 | KDM4E (0.34) | RAB9ASMN1; SMN2NPC1LMNARXFP1 | |
| SCHEMBL13645677 | 0.71 | COMT (0.32) | ALDH1A1LMNA | |
| SCHEMBL308028 | 0.71 | — | — | |
| SCHEMBL29772829 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994043-A | Preparation method of difluoro pyrazole acid | 湖南斯派克科技股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-117447401-B | Synthesis method of difluoro pyrazole acid | 山东国邦药业有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117447401-A | Synthesis method of difluoro pyrazole acid | 山东国邦药业有限公司 | 2024-01-26 | — | — | CN | disclosed |
| US-8785657-B2 | Processes for the preparation of pyrazoles | SYNGENTA CROP PROTECTION LLC (US) | 2014-07-22 | — | — | US | disclosed |
| US-8785657-B2 | Processes for the preparation of pyrazoles | SYNGENTA CROP PROTECTION LLC (US) | 2014-07-22 | — | — | US | disclosed |
| EP-1678141-B1 | 1,3-DIMETHYLBUTYL CARBOXANILIDES FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS | BAYER CROPSCIENCE AG (DE) | 2014-02-12 | — | — | EP | disclosed |
| EP-2192115-B1 | 1,3-DIMETHYLBUTYLCARBOXANILIDES FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS | BAYER CROPSCIENCE AG (DE) | 2014-02-12 | — | — | EP | disclosed |
| US-20130023668-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | SYNGENTA CROP PROTECTION, LLC (US) | 2013-01-24 | — | — | US | disclosed |
| US-20130023668-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | SYNGENTA CROP PROTECTION, LLC (US) | 2013-01-24 | — | — | US | disclosed |
| US-8269020-B2 | Processes for the preparation of pyrazoles | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-18 | — | — | US | disclosed |
| US-8269020-B2 | Processes for the preparation of pyrazoles | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-18 | — | — | US | disclosed |
| EP-2167461-B1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-08 | — | — | EP | disclosed |
| US-20100240907-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| US-20100240907-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-09-23 | — | — | US | disclosed |
| EP-2192115-A1 | 1,3-dimethylbutylcarboxanilides for controlling undesirable micro-organisms | Bayer CropScience AG (DE) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009000441-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-12-31 | — | — | WO | disclosed |
| EP-2008996-A1 | Process for the production of pyrazoles | Syngeta Participations AG (CH) | 2008-12-31 | — | — | EP | disclosed |
| EP-2008996-A1 | Process for the production of pyrazoles | Syngeta Participations AG (CH) | 2008-12-31 | — | — | EP | disclosed |
| EP-1678141-A1 | 1,3-DIMETHYLBUTYL CARBOXANILIDES FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS | Bayer CropScience Aktiengesellschaft (DE) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042492-A1 | 1,3-DIMETHYLBUTYL CARBOXANILIDES FOR CONTROLLING UNDESIRABLE MICRO-ORGANISMS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240907-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | CYP2F1, CYP4F3, CYP4F11 | RAB9A 815/4885SMN1; SMN2 4808/4885DUSP3 4265/4885 |
| US-20130023668-A1 | PROCESSES FOR THE PREPARATION OF PYRAZOLES | CYP2F1, CYP4F3, CYP4F11 | RAB9A 884/4885SMN1; SMN2 4827/4885DUSP3 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.