Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.80 |
| ▸ | MASP2 | O00187 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | POLB | P06746 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561722 | 0.89 | HCAR2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL125125 | 0.89 | HCAR2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL125126 | 0.89 | HCAR2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| Hydrochloric Acid SCHEMBL6744115 | 0.88 | HCAR2 (0.96) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL11433821 | 0.78 | HCAR2 (0.71) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL11433823 | 0.78 | HCAR2 (0.71) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL9222011 | 0.78 | HCAR2 (0.75) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL9222017 | 0.78 | HCAR2 (0.75) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL560440 | 0.77 | MASP2 (1.00) | HCAR2MASP2F2MAPTPOLB | |
| SCHEMBL560439 | 0.77 | MASP2 (1.00) | HCAR2MASP2F2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4577014-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| US-4501739-A | BACTERICIDES, ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
| US-4406898-A | ANTIBIOTICS CONTAINING A THIENOPYRIDINIUM OR FUROPYRIDINIUM GROUP | ELI LILLY AND COMPANY (US) | 1983-09-27 | — | — | US | disclosed |
| EP-0074268-A2 | Improvements in or relating to thieno and furopyridinium-substituted cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1983-03-16 | — | — | EP | disclosed |
| US-4071630-A | ANGINA PECTORIS | SANDOZ LTD. (CH) | 1978-01-31 | — | — | US | disclosed |