Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544752 | 0.84 | CSNK2A2 (0.49) | TSHRCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL1197245 | 0.83 | CSNK2A2 (0.45) | TSHRCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL4670497 | 0.83 | TSHR (0.52) | TSHRCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL6585808 | 0.83 | MAPT (0.39) | TSHRCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL10625935 | 0.83 | ALDH1A1 (0.37) | TSHRCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL7924637 | 0.83 | TSHR (0.47) | TSHRALDH1A1CASP1SMN1; SMN2LMNA | |
| SCHEMBL9586215 | 0.83 | SLC6A4 (0.39) | TSHRCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL4143093 | 0.81 | GRM1 (0.51) | TSHRCSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL4149318 | 0.81 | KMT2A (0.50) | CSNK2A2CSNK2BCSNK2A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3116286 | 0.81 | TSHR (0.45) | TSHRALDH1A1TP53CASP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57085336-A | — | — | None | — | — | JP | disclosed |
| CN-112409263-B | Substituted benzoyl compounds and application thereof | 东莞市东阳光农药研发有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-112409226-B | Substituted benzoyl compounds and application thereof | 东莞市东阳光农药研发有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-112142671-B | Substituted benzoyl-pyrazoles and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-112174889-B | Substituted benzoyl compounds and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-112430220-B | Substituted benzoyl compounds and application thereof | 东莞市东阳光农药研发有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-112300092-B | Heterocyclylalkyl-substituted dichlorobenzoyl compounds and application thereof | 东莞市东阳光农药研发有限公司 | 2023-06-09 | — | — | CN | disclosed |
| US-20230066771-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC (US) | 2023-03-02 | — | — | US | disclosed |
| US-20210130293-A1 | NUCLEAR RECEPTOR MODULATORS | ABBVIE INC (US) | 2021-05-06 | — | — | US | disclosed |
| WO-2021036845-A1 | SUBSTITUTED BENZOYL COMPOUND AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-03-04 | — | — | WO | disclosed |
| EP-0468766-A1 | Halogen-containing compounds, herbicidal composition containing the same as an active ingredient, and intermediary compounds therefor | Mitsubishi Chemical Corporation (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-4870182-A | 4-Hydroxy-quinoline-3-carboxylic | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| US-4804760-A | Process for the preparation of 4-hydroxy-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4762844-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0245690-A1 | Process for the preparation of 4-hydroxy-quinoline-3-carboxylic acids | BAYER AG (DE) | 1987-11-19 | — | — | EP | disclosed |
| EP-0181588-A2 | Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids, process for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-05-21 | — | — | EP | disclosed |
| US-4406688-A | Herbicidal 4-benzoyl-5-phenacyloxy-pyrazole derivatives, composition and method | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1983-09-27 | — | — | US | disclosed |
| JP-S5785336-A | 2,4-DICHLORO-M-TOLUIC ACID, ITS DERIVATIVE AND PREPARATION | MITSUBISHI PETROCHEM CO LTD | 1982-05-28 | — | — | JP | disclosed |
| US-4218464-A | 4- and 5-Substituted 2,3-dihydro-1H-isoindoles, pharmaceutical compositions and method of inhibiting phenylethanolamine N-methyltransferase | SMITHKLINE CORPORATION (US) | 1980-08-19 | — | — | US | disclosed |
| US-3985799-A | 2-Fluoro-6-trifluoromethylbenzoic acid | SANDOZ, INC. (US) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130293-A1 | NUCLEAR RECEPTOR MODULATORS | NR1I2, NR1H2, NR5A2 | TSHR 215/4885CSNK2A2 591/4885CSNK2B 629/4885 |
| US-20230066771-A1 | NUCLEAR RECEPTOR MODULATORS | NR1I2, NR1H2, NR5A2 | TSHR 215/4885CSNK2A2 591/4885CSNK2B 629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.