Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.65 |
| ▸ | HTR7 | P34969 | 4/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.65 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20562281 | 0.89 | HTR1A (0.64) | HTR1AHTR7DRD2MAPT | |
| SCHEMBL28714705 | 0.87 | DRD4 (0.49) | HTR1AHTR7KCNH2DRD2DRD4 | |
| SCHEMBL2881335 | 0.85 | HTR2A (0.52) | HTR1AHTR7KCNH2DRD2DRD4 | |
| SCHEMBL2881369 | 0.85 | HTR1A (0.57) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL2882030 | 0.85 | KDM4E (0.55) | HTR1AHTR7KCNH2DRD2DRD4 | |
| SCHEMBL5848982 | 0.84 | KCNH2 (0.75) | HTR1AHTR7KCNH2DRD2DRD3 | |
| SCHEMBL1374776 | 0.84 | MAPT (0.76) | HTR1AHTR7MAPT | |
| SCHEMBL7270516 | 0.83 | HTR1A (0.72) | HTR1AHTR7KCNH2DRD2DRD4 | |
| SCHEMBL11260878 | 0.83 | KCNH2 (0.73) | HTR1AHTR7KCNH2DRD2DRD3 | |
| SCHEMBL11247532 | 0.83 | KCNH2 (0.73) | HTR1AHTR7KCNH2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765950-B2 | Reagents for biomolecular labeling, detection and quantification employing raman spectroscopy | PURDUE RESEARCH FOUNDATION (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765950-B2 | Reagents for biomolecular labeling, detection and quantification employing raman spectroscopy | PURDUE RESEARCH FOUNDATION (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120107830-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | PURDUE RESEARCH FOUNDATION | 2012-05-03 | — | — | US | disclosed |
| US-20120107830-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | PURDUE RESEARCH FOUNDATION | 2012-05-03 | — | — | US | disclosed |
| US-8153827-B2 | Reagents for biomolecular labeling, detection and quantification employing Raman spectroscopy | PURDUE RESEARCH FOUNDATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153827-B2 | Reagents for biomolecular labeling, detection and quantification employing Raman spectroscopy | PURDUE RESEARCH FOUNDATION (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090219526-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-03 | — | — | US | disclosed |
| US-20090219526-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-03 | — | — | US | disclosed |
| WO-2009086509-A2 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | PURDUE RESEARCH FOUNDATION (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107830-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | SRMS, UQCRB, UQCRC1 | HTR1A 2848/4885HTR7 2612/4885KCNH2 3289/4885 |
| US-20090219526-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | SRMS, UQCRB, UQCRC1 | HTR1A 2422/4885HTR7 2525/4885KCNH2 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.