Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 13/20 | 0.40 |
| ▸ | BCHE | P06276 | 9/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11360362 | 0.85 | PRMT6 (0.55) | PRMT6ACHEBCHECHRM2HRH2 | |
| SCHEMBL11371642 | 0.81 | PRMT6 (0.62) | PRMT6ACHEBCHEHRH2 | |
| SCHEMBL10742212 | 0.80 | CYP1A2 (0.49) | PRMT6ACHEBCHEHRH2 | |
| SCHEMBL11214116 | 0.79 | PRMT6 (0.62) | PRMT6ACHEBCHE | |
| SCHEMBL11463439 | 0.78 | PRMT6 (0.50) | PRMT6ACHEBCHEHRH2 | |
| SCHEMBL11209167 | 0.78 | PRMT6 (0.50) | PRMT6ACHEBCHEHRH2 | |
| SCHEMBL10846891 | 0.78 | PRMT6 (0.50) | PRMT6ACHEBCHEHRH2 | |
| SCHEMBL10741444 | 0.78 | PRMT6 (0.61) | PRMT6ACHEBCHEHRH2CD274 | |
| SCHEMBL10847872 | 0.77 | PRMT6 (0.47) | PRMT6ACHEBCHE | |
| Hydrochloric Acid SCHEMBL11475500 | 0.77 | PRMT6 (0.49) | PRMT6ACHEBCHEHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4571398-A | Cytosine derivatives having histamine H2 -antagonist activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-02-18 | — | — | US | disclosed |
| US-4567176-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-01-28 | — | — | US | disclosed |