Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 9/20 | 0.35 |
| ▸ | BCHE | P06276 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919123 | 0.82 | PRMT6 (0.48) | PRMT6ACHEBCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL10857640 | 0.77 | PRMT6 (0.51) | PRMT6ACHEBCHE | |
| SCHEMBL11209657 | 0.77 | PRMT6 (0.51) | PRMT6ACHEBCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL11360362 | 0.74 | PRMT6 (0.55) | PRMT6ACHEBCHE | |
| SCHEMBL10849571 | 0.74 | ACHE (0.32) | HDAC6ACHEBCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL10846891 | 0.73 | PRMT6 (0.50) | PRMT6ACHEBCHEALDH1A1MEN1 | |
| SCHEMBL11463439 | 0.73 | PRMT6 (0.50) | PRMT6ACHEBCHE | |
| SCHEMBL11209167 | 0.73 | PRMT6 (0.50) | PRMT6ACHEBCHE | |
| SCHEMBL10741444 | 0.73 | PRMT6 (0.61) | PRMT6ACHEBCHE | |
| SCHEMBL10848949 | 0.72 | PRMT6 (0.49) | PRMT6ACHEBCHEALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567176-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-01-28 | — | — | US | disclosed |