Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.69 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.45 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CCND1 | P24385 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.45 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564762 | 0.89 | PBRM1 (0.69) | PBRM1CCNB2CCNE2CDK1CDK4 | |
| SCHEMBL3230702 | 0.84 | PBRM1 (0.71) | PBRM1ABCG2GFERTDP1KDM4E | |
| SCHEMBL7565777 | 0.83 | PBRM1 (0.69) | PBRM1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL10863663 | 0.83 | PBRM1 (0.69) | PBRM1CDK4CCND1CAMK2BCAMK2G | |
| SCHEMBL2444365 | 0.83 | PBRM1 (0.69) | PBRM1CDK9ABCG2GFERTDP1 | |
| SCHEMBL8143454 | 0.83 | PBRM1 (0.69) | PBRM1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL29801740 | 0.82 | PBRM1 (1.00) | PBRM1MEN1KMT2AABCG2GFER | |
| SCHEMBL4943278 | 0.82 | PBRM1 (1.00) | PBRM1MEN1KMT2AABCG2GFER | |
| SCHEMBL10861975 | 0.80 | HPGD (0.48) | PBRM1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL7571596 | 0.78 | PBRM1 (0.65) | PBRM1CCNE2CDK4CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4575553-A | 4'-(9-ACRIDINYLAMINO)-METHANESULFON-M-==ANISIDE | BRISTOL-MYERS COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
| EP-0165592-A2 | Antitumor agents | Bristol-Myers Company (US) | 1985-12-27 | — | — | EP | disclosed |