Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230702 | 0.84 | PBRM1 (0.71) | PBRM1KDM4EABCG2DYRK1A | |
| SCHEMBL10857797 | 0.83 | PBRM1 (0.69) | PBRM1KDM4EMEN1KMT2ACCNE2 | |
| SCHEMBL10863663 | 0.83 | PBRM1 (0.69) | PBRM1KDM4EMEN1KMT2ACDK4 | |
| SCHEMBL7565777 | 0.83 | PBRM1 (0.69) | PBRM1KDM4EMEN1LMNAHPGD | |
| SCHEMBL2444365 | 0.83 | PBRM1 (0.69) | PBRM1KDM4EABCG2DYRK1A | |
| SCHEMBL4943278 | 0.82 | PBRM1 (1.00) | PBRM1KDM4EMEN1LMNAHPGD | |
| SCHEMBL29801740 | 0.82 | PBRM1 (1.00) | PBRM1KDM4EMEN1LMNAHPGD | |
| SCHEMBL10857861 | 0.80 | PTGS2 (0.49) | PBRM1KDM4EHPGD | |
| SCHEMBL13940846 | 0.77 | DYRK1A (0.50) | PBRM1KDM4ELMNAHPGDCA1 | |
| SCHEMBL8122976 | 0.77 | MEN1 (0.46) | PBRM1KDM4EMEN1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001936-A1 | BIS -ACRIDINECARBOXAMIDE HAVING ANTI-TUMOR ACTIVITY | Universita degli Studi di Camerino (IT) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006372-A1 | BIS-ACRIDINECARBOXAMIDES HAVING ANTITUMOR ACTIVITY | UNIVERSITA' DEGLI STUDI DI CAMERINO (IT) | 1999-02-11 | — | — | WO | disclosed |
| WO-1999006405-A1 | PYRAZOLO-ACRIDINE DERIVATIVES HAVING ANTITUMOUR ACTIVITY | UNIVERSITA' DEGLI STUDI DI CAMERINO (IT) | 1999-02-11 | — | — | WO | disclosed |
| US-4575553-A | 4'-(9-ACRIDINYLAMINO)-METHANESULFON-M-==ANISIDE | BRISTOL-MYERS COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
| EP-0165592-A2 | Antitumor agents | Bristol-Myers Company (US) | 1985-12-27 | — | — | EP | disclosed |