Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733241 | 0.86 | CHRNA7 (0.52) | CHRNA7TDP1L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL4051277 | 0.83 | CYP1A2 (0.58) | L3MBTL1CYP1A2CYP2D6KMT2AALDH1A1 | |
| SCHEMBL8009737 | 0.81 | CHRNA7 (0.54) | CHRNA7TDP1L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL4965956 | 0.79 | CHRNA7 (0.56) | CHRNA7TDP1L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL4412493 | 0.78 | SIGMAR1 (0.63) | CYP1A2CYP2D6MEN1KMT2AALDH1A1 | |
| SCHEMBL9257762 | 0.77 | CHRNA7 (0.53) | CHRNA7TDP1L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL29403584 | 0.77 | ATM (0.57) | CHRNA7TDP1L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL883731 | 0.77 | ATM (0.57) | CHRNA7TDP1L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL22762044 | 0.77 | CYP1A2 (0.51) | CHRNA7TDP1L3MBTL1CYP2A6CYP1A2 | |
| SCHEMBL10311716 | 0.76 | HDAC8 (0.57) | L3MBTL1CYP1A2CYP2D6HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588735-A | Fungicidal (trihalophenoxy or trihalophenthio) alkylaminoalkyl pyridines and pyrroles | CHEVRON RESEARCH COMPANY (US) | 1986-05-13 | — | — | US | disclosed |