Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10861683 | 1.00 | MEN1 (0.50) | MEN1KMT2AMAPK1HSD17B10LMNA | |
| SCHEMBL10858817 | 0.85 | ALDH1A1 (0.62) | KMT2AHSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL10858811 | 0.85 | ALDH1A1 (0.62) | KMT2AHSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5888121 | 0.82 | HSD17B10 (0.56) | MEN1KMT2AMAPK1HSD17B10LMNA | |
| SCHEMBL1911514 | 0.82 | LMNA (0.56) | MEN1KMT2AMAPK1HSD17B10LMNA | |
| SCHEMBL2545875 | 0.80 | MAPK1 (0.47) | MEN1KMT2AMAPK1HSD17B10LMNA | |
| SCHEMBL2246989 | 0.80 | MAPK1 (0.47) | MEN1KMT2AMAPK1HSD17B10LMNA | |
| SCHEMBL10858808 | 0.80 | KDM4E (0.54) | MEN1KMT2AMAPK1HSD17B10LMNA | |
| SCHEMBL10858797 | 0.80 | KDM4E (0.54) | MEN1KMT2AMAPK1HSD17B10LMNA | |
| SCHEMBL17152434 | 0.80 | GAA (0.59) | MEN1KMT2AMAPK1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596803-A | Treating myocardial infarction | NIPPON CHEMIPHAR CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4507297-A | MYOCARDIAL INFARCTION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1985-03-26 | — | — | US | disclosed |