Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246989 | 1.00 | MAPK1 (0.47) | MAPK1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL2243308 | 0.87 | MMP2 (0.62) | MAPK1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL2549968 | 0.87 | MMP2 (0.62) | MAPK1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL2249019 | 0.86 | ALDH1A1 (0.58) | MAPK1HSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL2252745 | 0.86 | ALDH1A1 (0.58) | MAPK1HSD17B10KMT2AKDM4EALDH1A1 | |
| SCHEMBL2245819 | 0.82 | GRM1 (0.48) | MEN1KMT2AKDM4EALDH1A1TDP1 | |
| SCHEMBL10861692 | 0.80 | MEN1 (0.50) | MAPK1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL10861683 | 0.80 | MEN1 (0.50) | MAPK1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL7066752 | 0.79 | MEN1 (0.45) | MAPK1HSD17B10MEN1KMT2AKDM4E | |
| SCHEMBL7066749 | 0.79 | MEN1 (0.45) | MAPK1HSD17B10MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2011-10-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263628-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | HNMT, HCAR2, HPGD | MAPK1 2873/4885HSD17B10 126/4885MEN1 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.