SCHEMBL108619

SCHEMBL108619

C#Cc1cccc2c1C(=O)OC2=O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TYMS P04818 4/20 0.42
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72824 0.94 ALOX15 (0.40) ALOX15TDP1TYMSBRD4CREBBP
SCHEMBL2815250 0.91 ALOX15 (0.38) ALOX15TDP1TYMS
SCHEMBL2809225 0.84 ALOX15 (0.32) ALOX15TDP1TYMSBRD4CREBBP
Toluene SCHEMBL7860100 0.84 ALOX15 (0.36) ALOX15TDP1TYMS
SCHEMBL12814518 0.83 TDP1 (0.48) ALOX15TDP1TYMS
SCHEMBL19720181 0.81 ALOX15 (0.36) ALOX15TDP1TYMSBRD4CREBBP
SCHEMBL4959495 0.80 ALOX15 (0.44) ALOX15TDP1TYMS
SCHEMBL2810682 0.77 CYP1A2 (0.35)
SCHEMBL2710468 0.77 ALOX15 (0.41) ALOX15TDP1TYMS
SCHEMBL2810745 0.77 ALOX15 (0.37) ALOX15TDP1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039282-A Heterocyclic ethynyl phthalic anhydride derivative and synthetic method and application thereof 大连新阳光材料科技有限公司 2024-11-29 CN claimed
CN-118755086-A Thermosetting polyimide resin, preparation method thereof and composite material 中国科学院宁波材料技术与工程研究所 2024-10-11 CN claimed
CN-118344588-A High-temperature-resistant low-viscosity high-solubility polyisoimide resin and preparation method thereof 南京晨光集团有限责任公司 2024-07-16 CN claimed
CN-117624598-A VA type polyimide liquid crystal aligning agent, preparation method and application thereof 烟台显华高分子材料有限公司 2024-03-01 CN claimed
CN-117304484-A Polyimide prepolymer resin containing silicon and Cardo structure and preparation method thereof 大连理工大学 2023-12-29 CN claimed
CN-114230792-B Positive photosensitive polyimide resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-10-03 CN claimed
CN-116162436-A Low-dielectric and easily-dissolved polyisoimide adhesive and preparation method and application thereof 上海沥高科技股份有限公司 2023-05-26 CN claimed
CN-114891479-A Heat-resistant pressure-resistant rubber material and preparation method and application thereof 广东硕成科技股份有限公司 2022-08-12 CN claimed
CN-114230792-A Positive photosensitive polyimide resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-03-25 CN claimed
US-9868820-B2 Polyarylene materials ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-01-16 US claimed
US-20160060393-A1 POLYARYLENE MATERIALS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-03-03 US claimed
EP-2990430-A1 POLYARYLENE MATERIALS Rohm and Haas Electronic Materials LLC (US) 2016-03-02 EP claimed
WO-2015110502-A1 COMBINATION OF CROSS-LINKERS NEXAM CHEMICAL AB (SE) 2015-07-30 WO claimed
EP-2899179-A1 Combination of cross-linkers including carbon-carbon triple bonds Nexam Chemical AB (SE) 2015-07-29 EP claimed
EP-2569343-B1 CATALYSIS OF CROSS-LINKING NEXAM CHEMICAL AB (SE) 2015-07-08 EP claimed
US-20140356703-A1 ELECTROCHEMICAL CELL COMPRISING A NANOWEB COMPRISING NANOFIBERS OF A CROSS-LINKED POLYIMIDE E. I. DU PONT DE NEMOURS AND COMPANY 2014-12-04 US claimed
WO-2013181333-A1 AN ELECTROCHEMICAL CELL COMPRISING A NANOWEB COMPRISING NANOFIBERS OF A CROSS-LINKED POLYIMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-12-05 WO claimed
CN-101307004-B Polyfluorphenyl substituted aromatic diamine, polymers thereof and method for preparing same CHINESE ACAD INST CHEMISTRY 2011-08-31 CN claimed
CN-101307004-A Polyfluorphenyl substituted aromatic diamine, polymers thereof and method for preparing same CHINESE ACAD INST CHEMISTRY (CN) 2008-11-19 CN claimed
US-5066771-A Endcapped with triple bonds, made from aromatic acid and amine, self-curing, polyimide properties, soluble in organic solvents KOZO IIZUKA, DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1991-11-19 US claimed