SCHEMBL2809225

SCHEMBL2809225

C#Cc1cccc2c1C(=O)OC2=O.C1CC2CC2C1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TYMS P04818 1/20 0.32
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108619 0.84 ALOX15 (0.44) ALOX15TDP1TYMSBRD4CREBBP
SCHEMBL72824 0.80 ALOX15 (0.40) ALOX15TDP1TYMSBRD4CREBBP
SCHEMBL2815250 0.77 ALOX15 (0.38) ALOX15TDP1TYMS
SCHEMBL2810682 0.73 CYP1A2 (0.35)
Trifluoromethylbenzene SCHEMBL27881692 0.71 ALDH1A1 (0.40) ALOX15TDP1TYMS
Toluene SCHEMBL7860100 0.71 ALOX15 (0.36) ALOX15TDP1TYMS
SCHEMBL12814518 0.70 TDP1 (0.48) ALOX15TDP1TYMS
SCHEMBL2809219 0.70 CREBBP (0.45) ALOX15TDP1TYMSBRD4CREBBP
SCHEMBL19720181 0.68 ALOX15 (0.36) ALOX15TDP1TYMSBRD4CREBBP
SCHEMBL4959495 0.68 ALOX15 (0.44) ALOX15TDP1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221935-A Polyamide acid slurry with low water absorption rate and polyimide film prepared from polyamide acid slurry 武汉柔显科技股份有限公司 2024-06-21 CN claimed
CN-118221935-A Polyamide acid slurry with low water absorption rate and polyimide film prepared from polyamide acid slurry 武汉柔显科技股份有限公司 2024-06-21 CN disclosed
US-20100240908-A1 ACETYLENE COMPOUND FUJIFILM CORPORATION (JP) 2010-09-23 US disclosed
EP-2202221-A1 ACETYLENE COMPOUND Fujifilm Corporation (JP) 2010-06-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240908-A1 ACETYLENE COMPOUND NAT1, KATNA1, KAT2B ALOX15 1994/4885TDP1 4533/4885TYMS 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.