SCHEMBL4959495

SCHEMBL4959495

N#Cc1cccc2c1C(=O)OC2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TYMS P04818 3/20 0.42
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
USP8 P40818 1/20 0.40
USP7 Q93009 1/20 0.40
PDK2 Q15119 1/20 0.39
MCL1 Q07820 1/20 0.38
ESR2 Q92731 1/20 0.36
GRIA1 P42261 1/20 0.36
CACNG8 Q8WXS5 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
TSHR P16473 1/20 0.34
ALDH1A1 P00352 1/20 0.34
DRD2 P14416 1/20 0.34
DGAT1 O75907 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12814518 0.83 TDP1 (0.48) ALOX15TDP1TYMSTSHRALDH1A1
SCHEMBL108619 0.80 ALOX15 (0.44) ALOX15TDP1TYMS
SCHEMBL2710468 0.77 ALOX15 (0.41) ALOX15TDP1TYMSTSHRALDH1A1
SCHEMBL8486849 0.77 USP8 (0.48) ALOX15TDP1CA1CA2USP8
SCHEMBL72824 0.76 ALOX15 (0.40) ALOX15TDP1TYMS
SCHEMBL28781829 0.76 ALOX15 (0.33) ALOX15TDP1TYMSUSP8USP7
SCHEMBL31548711 0.75 TDP1 (0.60) ALOX15TDP1TYMSMCL1MEN1
SCHEMBL2087097 0.75 TDP1 (0.60) ALOX15TDP1TYMSMCL1MEN1
SCHEMBL2810259 0.74 CREBBP (0.39) ALOX15TDP1TYMSMEN1KMT2A
SCHEMBL29546502 0.74 ALOX15 (0.43) ALOX15TDP1TYMSCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929662-B Succinimide or maleimide compound and use thereof 中国医学科学院药物研究所 2023-01-06 CN disclosed
CN-113956236-B Phthalimide compound and application thereof 中国医学科学院药物研究所 2023-01-06 CN disclosed
CN-109867661-B Amide compounds for regulating WNT signal pathway and application thereof 中国医学科学院药物研究所 2022-07-19 CN disclosed
CN-113956236-A Phthalimide compound and application thereof 中国医学科学院药物研究所 2022-01-21 CN disclosed
CN-113929662-A Succinimide or maleimide compound and use thereof 中国医学科学院药物研究所 2022-01-14 CN disclosed
CN-109867661-A Adjust the amides compound and application thereof of WNT signal path 中国医学科学院药物研究所 2019-06-11 CN disclosed
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 WO disclosed
US-5770340-A USING ELECTROGRAPHIC PRINTING PLATE HAVING ELECTROCONDUCTIVE SUPPORT WITH PHOTOCONDUCTIVE LAYER CONTAINING INORGANIC PHOTOCONDUCTOR, SPECIFIC SENSITIZING DYE AND BINDER, ALSO WITH BACKING HAVING LOW ELECTRICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1998-06-23 US disclosed
US-5677098-A USING CYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1997-10-14 US disclosed
US-5370956-A With layer containing inorganic photoconductor, binder and sensitizing dye, high sensitivity to red light, storage stability, for scanning exposure with semiconductor laser beam MITSUBISHI PAPER MILLS LIMITED (JP) 1994-12-06 US disclosed
EP-0288083-B1 Method of image formation which includes scanning exposure process FUJI PHOTO FILM CO LTD (JP) 1994-08-10 EP disclosed
US-4929527-A DARK CHARGE RETAINING PROPERTIES FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
EP-0288083-A2 Method of image formation which includes scanning exposure process FUJI PHOTO FILM CO., LTD. (JP) 1988-10-26 EP disclosed
US-4496711-A CYCLIZATION AT LOW TEMPERATURES THE REACTION PRODUCT ON AN ANHYDRIDE, DIAMINE AND AMINE-CONTAINING ACETYLENE OR NITRILE HUGHES AIRCRAFT COMPANY (US) 1985-01-29 US disclosed
US-4495342-A Isoimide containing oligomers HUGHES AIRCRAFT COMPANY (US) 1985-01-22 US disclosed
US-4485231-A ADDITION POLYMERIZABLE HUGHES AIRCRAFT COMPANY (US) 1984-11-27 US disclosed