Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.67 |
| ▸ | GABRP | O00591 | 1/20 | 0.60 |
| ▸ | GABRD | O14764 | 1/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.60 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.60 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.60 |
| ▸ | GABRE | P78334 | 1/20 | 0.60 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.60 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.60 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.60 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10712253 | 0.92 | ADORA3 (0.63) | ADORA3XDHGABRPGABRDGABRA1 | |
| SCHEMBL3564388 | 0.91 | GABRP (0.72) | ADORA3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22979500 | 0.90 | GABRP (0.74) | XDHGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29646336 | 0.90 | GABRP (0.74) | XDHGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10713041 | 0.86 | ADORA3 (0.62) | ADORA3XDHGABRPGABRDGABRA1 | |
| SCHEMBL3567661 | 0.84 | ADORA3 (0.62) | ADORA3XDHGABRPGABRDGABRA1 | |
| SCHEMBL10715388 | 0.84 | ADORA3 (0.62) | ADORA3XDHGABRPGABRDGABRA1 | |
| SCHEMBL3571863 | 0.83 | KDM4E (0.63) | ADORA3XDHGABRPGABRDGABRA1 | |
| SCHEMBL10714714 | 0.82 | ADORA3 (0.66) | ADORA3GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22987949 | 0.81 | KDM4E (0.72) | ADORA3XDHKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181282-A1 | Triazoloquinazoline compounds | CIBA-GEIGY AG (CH) | 1986-05-14 | — | — | EP | disclosed |