Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | NPC1 | O15118 | 4/20 | 0.83 |
| ▸ | RAB9A | P51151 | 4/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | USP2 | O75604 | 3/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | THRB | P10828 | 2/20 | 0.83 |
| ▸ | PKM | P14618 | 2/20 | 0.83 |
| ▸ | XBP1 | P17861 | 2/20 | 0.83 |
| ▸ | HTT | P42858 | 2/20 | 0.83 |
| ▸ | RECQL | P46063 | 2/20 | 0.83 |
| ▸ | BLM | P54132 | 2/20 | 0.83 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.83 |
| ▸ | ALPG | P10696 | 1/20 | 0.83 |
| ▸ | CRHBP | P24387 | 1/20 | 0.83 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10864242 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL29461580 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL29461678 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10137818 | 0.99 | MEN1 (0.84) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10036027 | 0.99 | MEN1 (0.84) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL31018273 | 0.96 | MEN1 (0.90) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL29419520 | 0.96 | MEN1 (0.90) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8603487 | 0.95 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13873490 | 0.95 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10137808 | 0.95 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600625-A | Optical information recording medium | RICOH CO., LTD. (JP) | 1986-07-15 | — | — | US | disclosed |