Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.92 |
| ▸ | MAPT | P10636 | 4/20 | 0.92 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.92 |
| ▸ | NPC1 | O15118 | 3/20 | 0.92 |
| ▸ | RAB9A | P51151 | 3/20 | 0.92 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.92 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.92 |
| ▸ | USP2 | O75604 | 2/20 | 0.92 |
| ▸ | LMNA | P02545 | 2/20 | 0.92 |
| ▸ | POLB | P06746 | 2/20 | 0.92 |
| ▸ | THRB | P10828 | 2/20 | 0.92 |
| ▸ | PKM | P14618 | 2/20 | 0.92 |
| ▸ | XBP1 | P17861 | 2/20 | 0.92 |
| ▸ | HTT | P42858 | 2/20 | 0.92 |
| ▸ | RECQL | P46063 | 2/20 | 0.92 |
| ▸ | BLM | P54132 | 2/20 | 0.92 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.92 |
| ▸ | ALPG | P10696 | 1/20 | 0.92 |
| ▸ | CRHBP | P24387 | 1/20 | 0.92 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603487 | 1.00 | MEN1 (0.92) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL13873490 | 1.00 | MEN1 (0.92) | MEN1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL29419520 | 0.99 | MEN1 (0.90) | MEN1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL31018273 | 0.99 | MEN1 (0.90) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL10036027 | 0.96 | MEN1 (0.84) | MEN1MAPTKMT2ANPC1RAB9A | |
| SCHEMBL10137818 | 0.96 | MEN1 (0.84) | MEN1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL10864242 | 0.95 | MEN1 (0.83) | MEN1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL10864237 | 0.95 | MEN1 (0.83) | MEN1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL29461678 | 0.95 | MEN1 (0.83) | MEN1MAPTKMT2ANPC1RAB9A | |
| Iodide SCHEMBL29461580 | 0.95 | MEN1 (0.83) | MEN1MAPTKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781675-B1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES INC (US) | 2014-03-26 | — | — | EP | disclosed |
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |
| US-8008522-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2011-08-30 | — | — | US | disclosed |
| US-20110165085-A1 | TUMOR SELECTIVE FLUORESCENT STAINING AGENT | THE UNIVERSITY OF TOKYO (JP) | 2011-07-07 | — | — | US | disclosed |
| US-20110070166-A1 | REDUCED DYE PROBES FOR THE DETECTION OF RADICAL OXYGEN SPECIES | GEORGIA TECH RESEARCH CORPORATION | 2011-03-24 | — | — | US | disclosed |
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2010-10-14 | — | — | US | disclosed |
| US-7767834-B2 | Phosphonylated fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2010-08-03 | — | — | US | disclosed |
| US-7671218-B2 | Phosphonate fluorescent dyes and conjugates | Elitech Holdings B.V. (NL) | 2010-03-02 | — | — | US | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261903-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | MEN1 1647/4885MAPT 1477/4885KMT2A 3091/4885 |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | MEN1 1539/4885MAPT 1921/4885KMT2A 3036/4885 |
| US-20110070166-A1 | REDUCED DYE PROBES FOR THE DETECTION OF RADICAL OXYGEN SPECIES | ROS1, GPX4, DHRS9 | MEN1 3431/4885MAPT 4531/4885KMT2A 3839/4885 |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | MEN1 1647/4885MAPT 1477/4885KMT2A 3091/4885 |
| US-20110165085-A1 | TUMOR SELECTIVE FLUORESCENT STAINING AGENT | TPD52L2, MKI67, CD68 | MEN1 156/4885MAPT 4690/4885KMT2A 2811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.