Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.83 |
| ▸ | NPC1 | O15118 | 4/20 | 0.83 |
| ▸ | RAB9A | P51151 | 4/20 | 0.83 |
| ▸ | MAPT | P10636 | 4/20 | 0.83 |
| ▸ | USP2 | O75604 | 3/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | POLB | P06746 | 2/20 | 0.83 |
| ▸ | THRB | P10828 | 2/20 | 0.83 |
| ▸ | PKM | P14618 | 2/20 | 0.83 |
| ▸ | XBP1 | P17861 | 2/20 | 0.83 |
| ▸ | HTT | P42858 | 2/20 | 0.83 |
| ▸ | RECQL | P46063 | 2/20 | 0.83 |
| ▸ | BLM | P54132 | 2/20 | 0.83 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.83 |
| ▸ | ALPG | P10696 | 1/20 | 0.83 |
| ▸ | CRHBP | P24387 | 1/20 | 0.83 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10864237 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL10864242 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL29461678 | 1.00 | MEN1 (0.83) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10137818 | 0.99 | MEN1 (0.84) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10036027 | 0.99 | MEN1 (0.84) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL31018273 | 0.96 | MEN1 (0.90) | MEN1KMT2ANPC1RAB9AMAPT | |
| Iodide SCHEMBL29419520 | 0.96 | MEN1 (0.90) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8603487 | 0.95 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL13873490 | 0.95 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL10137808 | 0.95 | MEN1 (0.92) | MEN1KMT2ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637489-B2 | Silicon containing modified nucleotide analogs | Singular Genomics Systems, Inc. (US) | 2026-05-26 | — | — | US | disclosed |
| US-12630808-B2 | Modified archaeal family b polymerases | Singular Genomics Systems, Inc. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-04-23 | — | — | US | disclosed |
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-04-07 | — | — | US | disclosed |
| US-20260085299-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-03-26 | — | — | US | disclosed |
| US-12577271-B2 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2026-03-17 | — | — | US | disclosed |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | SINGULAR GENOMICS SYSTEMS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-20260015402-A1 | SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN RECEPTOR BEARING T CELLS (SMART CARS) | YALE UNIVERSITY | 2026-01-15 | — | — | US | disclosed |
| US-12503730-B2 | Detectable nucleotide analogues | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-12-23 | — | — | US | disclosed |
| EP-3705609-B1 | DETECTION OF NUCLEIC ACIDS | UNIV MICHIGAN REGENTS (US) | 2022-06-08 | — | — | EP | disclosed |
| US-20220170092-A1 | METHODS FOR LONG READ SEQUENCING | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-06-02 | — | — | US | disclosed |
| EP-3997101-A1 | NOVEL NUCLEOTIDE ANALOGUES AND METHODS FOR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-18 | — | — | EP | disclosed |
| US-11318470-B2 | Microfluidics-based nanobiosensors and devices | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2022-05-03 | — | — | US | disclosed |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | LG ELECTRONICS INC. (KR) | 2022-04-28 | — | — | US | disclosed |
| US-20220119780-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| US-20220119779-A1 | MODIFIED PYROCOCCUS POLYMERASES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-04-21 | — | — | US | disclosed |
| WO-2022072374-A1 | LIGHT-CONTROLLED BIOORTHOGONAL TETRAZINE LIGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-07 | — | — | WO | disclosed |
| US-11279982-B2 | EGFR assay | ABBOTT MOLECULAR INC. (US) | 2022-03-22 | — | — | US | disclosed |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260015402-A1 | SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN RECEPTOR BEARING T CELLS (SMART CARS) | CD2, CD74, CD2BP2 | MEN1 4655/4885KMT2A 1820/4885NPC1 3291/4885 |
| US-12630808-B2 | Modified archaeal family b polymerases | SSU72, POLB, POLQ | MEN1 3513/4885KMT2A 308/4885NPC1 4374/4885 |
| US-12595508-B2 | Nucleotide cleavable linkers and uses thereof | NSUN2, CCRL2, NOP2 | MEN1 4378/4885KMT2A 2804/4885NPC1 248/4885 |
| US-12577271-B2 | Modified nucleotides and uses thereof | NUDT1, NSUN2, CCRL2 | MEN1 2476/4885KMT2A 2809/4885NPC1 93/4885 |
| US-12637489-B2 | Silicon containing modified nucleotide analogs | NSUN2, POLR2H, POLH | MEN1 2394/4885KMT2A 2375/4885NPC1 256/4885 |
| US-20260110028-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | POLL, POLB, POLN | MEN1 3638/4885KMT2A 1209/4885NPC1 3739/4885 |
| US-20220127299-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | NUDT21, CPSF7, DCLRE1A | MEN1 2454/4885KMT2A 1435/4885NPC1 2262/4885 |
| US-20260085299-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | POLB, POLM, POLRMT | MEN1 1571/4885KMT2A 1696/4885NPC1 4713/4885 |
| US-20260028667-A1 | NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF | POLN, NSUN2, POLL | MEN1 2600/4885KMT2A 1592/4885NPC1 1784/4885 |
| US-20260125660-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | DNMT3A, POLB, POLM | MEN1 2077/4885KMT2A 755/4885NPC1 4833/4885 |
| US-12503730-B2 | Detectable nucleotide analogues | NT5C3B, NUDT1, RNGTT | MEN1 2733/4885KMT2A 3544/4885NPC1 666/4885 |
| US-11266673-B2 | Nucleotide derivatives and methods of use thereof | POLRMT, NSUN2, NUDT1 | MEN1 3223/4885KMT2A 1863/4885NPC1 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.