Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667085 | 0.67 | MAPT (0.44) | HTTMAPTMEN1ALDH1A1POLB | |
| SCHEMBL1669188 | 0.67 | ALDH1A1 (0.50) | HTTHPGDMAPTRXFP1MEN1 | |
| SCHEMBL62657 | 0.62 | CA12 (0.59) | HTTHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL204877 | 0.62 | CA12 (0.59) | HTTHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL9097535 | 0.62 | CA12 (0.59) | HTTHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL9468327 | 0.61 | GAA (0.53) | HTTHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL28837137 | 0.61 | HSD17B10 (0.41) | HTTHPGDMAPTRXFP1MEN1 | |
| Hydrochloric Acid SCHEMBL8640288 | 0.61 | CA12 (0.57) | HTTHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL28143119 | 0.60 | HTT (0.50) | HTTHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL203108 | 0.60 | PBRM1 (0.67) | HTTHPGDMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194529-A2 | Use of 2-(aminophenyl)-benzimidazole derivatives in the preparation of medicaments for combating malign and non-malign proliferative as well as auto-immune diseases and in immunosuppression in transplantations | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |